Hs03650832_cn

• Gene Symbol: YWHAG
• Assay Reference Genome Location: Chr.7:76343469 on build GRCh38
• Cytoband: 7q11.23

Target Gene Details

• Entrez Gene ID: 7532
• Gene Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
• Gene Aliases: 14-3-3GAMMA, PPP1R170
• Location: Chr.7:76326791-76359025 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
YWHAG	NM_012479.3			NP_036611.2
	AB024334.1			BAA85184.1
	AF142498.1			AAD48408.1
	AK024230.1
	AK293505.1
	AK295029.1
	BC020963.2			AAH20963.1
	CR541904.1			CAG46702.1
	CR541925.1			CAG46723.1
	DC343104.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2422494	Chr.7:76286900 - 76984449 on Build GRCh38	Duplication	SRRM3 POMZP3 DTX2 LOC105375355 HSPB1 SPDYE16 SSC4D LOC100133091 DTX2P1-UPK3BP1-PMS2P11 ZP3 YWHAG FDPSP2
nsv528969	Chr.7:75074053 - 76920728 on Build GRCh38	Gain	SRRM3 MIR4651 STYXL1 DTX2 LOC105375355 LOC100133091 SPDYE5 YWHAG TMEM120A NCF1C PMS2P2 SNORA14A TRIM73 HSPB1 SSC4D PMS2P3 ZP3 CCL26 LOC441259 NSUN5P1 FDPSP2 MDH2 POMZP3 HIP1 SPDYE16 POM121C GTF2IP1 GTF2IRD2B LOC541473 RHBDD2 GTF2IP7 PMS2P10 CCL24 STAG3L1 LOC107986711 POR
nsv428174	Chr.7:76305019 - 77220062 on Build GRCh38	Gain	POMZP3 DTX2 LOC105375355 SPDYE16 LOC100133091 DTX2P1-UPK3BP1-PMS2P11 PMS2P9 SPDYE18 YWHAG SPDYE17 FGL2 SSC4D CCDC146 ZP3 FDPSP2
nsv1028665	Chr.7:76336044 - 76445651 on Build GRCh38	Gain	SSC4D ZP3 YWHAG
dgv120n16	Chr.7:75440769 - 76641919 on Build GRCh38	Deletion	SRRM3 MIR4651 STYXL1 DTX2 LOC105375355 LOC100133091 SPDYE5 YWHAG TMEM120A SNORA14A HSPB1 SSC4D PMS2P3 ZP3 CCL26 FDPSP2 MDH2 POMZP3 HIP1 SPDYE16 POM121C RHBDD2 GTF2IP7 CCL24 LOC107986711 POR

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

G2/M transition of mitotic cell cycle
negative regulation of protein kinase activity
protein targeting
regulation of signal transduction
cellular response to insulin stimulus
regulation of neuron differentiation
regulation of synaptic plasticity
membrane organization
negative regulation of protein serine/threonine kinase activity
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

Function(s)

protein kinase C binding
insulin-like growth factor receptor binding
protein binding
protein kinase C inhibitor activity
protein domain specific binding
receptor tyrosine kinase binding
poly(A) RNA binding