Hs03653142_cn

• Gene Symbol: YWHAG
• Assay Reference Genome Location: Chr.7:76343937 on build GRCh38
• Cytoband: 7q11.23

Target Gene Details

• Entrez Gene ID: 7532
• Gene Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
• Gene Aliases: 14-3-3GAMMA, PPP1R170
• Location: Chr.7:76326791-76359025 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
YWHAG	NM_012479.3			NP_036611.2
	AB024334.1			BAA85184.1
	AF142498.1			AAD48408.1
	AK024230.1
	AK293505.1
	AK295029.1
	BC020963.2			AAH20963.1
	CR541904.1			CAG46702.1
	CR541925.1			CAG46723.1
	DC343104.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2422494	Chr.7:76286900 - 76984449 on Build GRCh38	Duplication	SSC4D ZP3 LOC100133091 DTX2P1-UPK3BP1-PMS2P11 YWHAG SRRM3 HSPB1 FDPSP2 SPDYE16 DTX2 POMZP3 LOC105375355
nsv528969	Chr.7:75074053 - 76920728 on Build GRCh38	Gain	SSC4D CCL24 PMS2P3 MDH2 FDPSP2 NCF1C GTF2IP7 LOC105375355 RHBDD2 YWHAG LOC107986711 MIR4651 SRRM3 LOC441259 NSUN5P1 SPDYE16 DTX2 POMZP3 POM121C PMS2P10 ZP3 LOC100133091 TRIM73 TMEM120A CCL26 SNORA14A SPDYE5 PMS2P2 HIP1 LOC541473 STYXL1 GTF2IRD2B GTF2IP1 HSPB1 STAG3L1 POR
nsv428174	Chr.7:76305019 - 77220062 on Build GRCh38	Gain	SSC4D ZP3 LOC100133091 SPDYE18 SPDYE17 FDPSP2 LOC105375355 DTX2P1-UPK3BP1-PMS2P11 YWHAG FGL2 SPDYE16 CCDC146 PMS2P9 DTX2 POMZP3
nsv1028665	Chr.7:76336044 - 76445651 on Build GRCh38	Gain	SSC4D ZP3 YWHAG
dgv120n16	Chr.7:75440769 - 76641919 on Build GRCh38	Deletion	SSC4D CCL24 PMS2P3 MDH2 FDPSP2 GTF2IP7 LOC105375355 RHBDD2 YWHAG LOC107986711 MIR4651 SRRM3 SPDYE16 DTX2 POMZP3 POM121C ZP3 LOC100133091 TMEM120A CCL26 SNORA14A SPDYE5 HIP1 STYXL1 HSPB1 POR

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

G2/M transition of mitotic cell cycle
negative regulation of protein kinase activity
protein targeting
regulation of signal transduction
cellular response to insulin stimulus
regulation of neuron differentiation
regulation of synaptic plasticity
membrane organization
negative regulation of protein serine/threonine kinase activity
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

Function(s)

protein kinase C binding
insulin-like growth factor receptor binding
protein binding
protein kinase C inhibitor activity
protein domain specific binding
receptor tyrosine kinase binding
poly(A) RNA binding