Hs03654585_cn

• Gene Symbol: YWHAG
• Assay Reference Genome Location: Chr.7:76353053 on build GRCh38
• Cytoband: 7q11.23

Target Gene Details

• Entrez Gene ID: 7532
• Gene Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
• Gene Aliases: 14-3-3GAMMA, PPP1R170
• Location: Chr.7:76326791-76359025 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
YWHAG	NM_012479.3			NP_036611.2
	AB024334.1			BAA85184.1
	AF142498.1			AAD48408.1
	AK024230.1
	AK293505.1
	AK295029.1
	BC020963.2			AAH20963.1
	CR541904.1			CAG46702.1
	CR541925.1			CAG46723.1
	DC343104.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2422494	Chr.7:76286900 - 76984449 on Build GRCh38	Duplication	SRRM3 ZP3 SPDYE16 DTX2P1-UPK3BP1-PMS2P11 FDPSP2 HSPB1 DTX2 LOC105375355 POMZP3 LOC100133091 YWHAG SSC4D
nsv528969	Chr.7:75074053 - 76920728 on Build GRCh38	Gain	STYXL1 SPDYE5 LOC107986711 GTF2IRD2B HSPB1 HIP1 LOC541473 POMZP3 STAG3L1 NCF1C GTF2IP7 SPDYE16 FDPSP2 DTX2 TMEM120A POM121C ZP3 CCL26 GTF2IP1 NSUN5P1 PMS2P2 MIR4651 SSC4D PMS2P3 SRRM3 TRIM73 CCL24 SNORA14A MDH2 PMS2P10 LOC441259 LOC105375355 POR RHBDD2 LOC100133091 YWHAG
nsv428174	Chr.7:76305019 - 77220062 on Build GRCh38	Gain	ZP3 SPDYE17 DTX2P1-UPK3BP1-PMS2P11 POMZP3 SSC4D PMS2P9 SPDYE16 FDPSP2 CCDC146 FGL2 DTX2 LOC105375355 LOC100133091 YWHAG SPDYE18
nsv1028665	Chr.7:76336044 - 76445651 on Build GRCh38	Gain	ZP3 YWHAG SSC4D
dgv120n16	Chr.7:75440769 - 76641919 on Build GRCh38	Deletion	STYXL1 SPDYE5 LOC107986711 HSPB1 HIP1 POMZP3 GTF2IP7 SPDYE16 FDPSP2 DTX2 TMEM120A POM121C ZP3 CCL26 MIR4651 SSC4D PMS2P3 SRRM3 CCL24 SNORA14A MDH2 LOC105375355 POR RHBDD2 LOC100133091 YWHAG

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

G2/M transition of mitotic cell cycle
negative regulation of protein kinase activity
protein targeting
regulation of signal transduction
cellular response to insulin stimulus
regulation of neuron differentiation
regulation of synaptic plasticity
membrane organization
negative regulation of protein serine/threonine kinase activity
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

Function(s)

protein kinase C binding
insulin-like growth factor receptor binding
protein binding
protein kinase C inhibitor activity
protein domain specific binding
receptor tyrosine kinase binding
poly(A) RNA binding