Hs03659943_cn

• Gene Symbol: LYPLA1
• Assay Reference Genome Location: Chr.8:54049874 on build GRCh38
• Cytoband: 8q11.23

Target Gene Details

• Entrez Gene ID: 10434
• Gene Name: lysophospholipase I
• Gene Aliases: APT-1, APT1, LPL-I, LPL1, hAPT1
• Location: Chr.8:54046367-54102017 on Build GRCh38
• Assay Gene Location: Within Intron 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LYPLA1	NM_001279356.1			NP_001266285.1
	NM_001279357.1			NP_001266286.1
	NM_001279358.1			NP_001266287.1
	NM_001279359.1			NP_001266288.1
	NM_001279360.1			NP_001266289.1
	NM_006330.3			NP_006321.1
	XM_005251127.4			XP_005251184.1
	XM_017012956.1			XP_016868445.1
	XM_017012957.1			XP_016868446.1
	XM_017012958.1			XP_016868447.1
	XM_017012959.1			XP_016868448.1
	XM_017012960.1			XP_016868449.1
	AF035293.1			AAB88180.1
	AF052112.1
	AF077198.1			AAD26993.1
	AF077199.1			AAD26994.1
	AF081281.1			AAC31610.1
	AF291053.1			AAG10063.1
	AK289400.1
	AK298206.1
	AK313739.1
	BC008652.2			AAH08652.1
	BC010397.1			AAH10397.1
	CR457103.1			CAG33384.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3576573	Chr.8:53946867 - 54052964 on Build GRCh38	Gain	RGS20 TCEA1 LOC105375839 LYPLA1
esv2759617	Chr.8:53920430 - 54104405 on Build GRCh38	Gain	RGS20 TCEA1 LOC105375839 LYPLA1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

phospholipase

Gene Ontology Categories:

Process(es)

protein depalmitoylation
fatty acid metabolic process
negative regulation of Golgi to plasma membrane protein transport
regulation of nitric-oxide synthase activity

Function(s)

lysophospholipase activity
palmitoyl-(protein) hydrolase activity
lipase activity