Hs03688129_cn

• Gene Symbol: BOP1
• Assay Reference Genome Location: Chr.8:144282807 on build GRCh38
• Cytoband: 8q24.3

Target Gene Details

• Entrez Gene ID: 23246
• Gene Name: block of proliferation 1
• Gene Aliases: -
• Location: Chr.8:144262046-144291438 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
BOP1	NM_015201.4			NP_056016.1
	AB060694.1			BAB70666.1
	AK024840.1
	AK290677.1
	AK293719.1
	AK315612.1
	BC001086.2			AAH01086.2
	BC005160.2			AAH05160.2
	BC007274.1			AAH07274.1
	BC013787.1			AAH13787.1
	BC013980.2			AAH13980.1
	BC017674.2			AAH17674.1
	BQ711345.1
	D50914.1			BAA09473.1
	DA510177.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv470249	Chr.8:143889098 - 144519234 on Build GRCh38	Loss	MFSD3 FOXH1 ADCK5 MIR6848 DGAT1 MAF1 SHARPIN GRINA CYC1 SLC39A4 MIR939 TMEM249 SLC52A2 LRRC14 FBXL6 PPP1R16A SCX LOC101928953 MIR661 TONSL-AS1 CPSF1 EXOSC4 PLEC RECQL4 MIR6893 GPAA1 MIR7112 VPS28 SMPD5 SCRT1 MIR1234 MIR6849 HSF1 BOP1 WDR97 LOC101928902 PARP10 HGH1 SPATC1 TONSL MIR6847 CYHR1 KIFC2 MIR6846 MROH1 GPT OPLAH
dgv12434n54	Chr.8:144270080 - 144516801 on Build GRCh38	Loss	MFSD3 FOXH1 ADCK5 MIR6848 DGAT1 SLC39A4 MIR939 TMEM249 SLC52A2 FBXL6 PPP1R16A LOC101928953 TONSL-AS1 CPSF1 RECQL4 MIR6893 VPS28 SCRT1 MIR1234 MIR6849 HSF1 BOP1 LOC101928902 TONSL CYHR1 KIFC2 GPT
nsv515809	Chr.8:143904439 - 144519234 on Build GRCh38	Gain+Loss	MFSD3 FOXH1 ADCK5 MIR6848 DGAT1 MAF1 SHARPIN GRINA CYC1 SLC39A4 MIR939 TMEM249 SLC52A2 LRRC14 FBXL6 PPP1R16A SCX LOC101928953 MIR661 TONSL-AS1 CPSF1 EXOSC4 PLEC RECQL4 MIR6893 GPAA1 MIR7112 VPS28 SMPD5 SCRT1 MIR1234 MIR6849 HSF1 BOP1 WDR97 LOC101928902 PARP10 HGH1 SPATC1 TONSL MIR6847 CYHR1 KIFC2 MIR6846 MROH1 GPT OPLAH
nsv428208	Chr.8:144041826 - 144722291 on Build GRCh38	Gain	LRRC24 MFSD3 FOXH1 ADCK5 MIR6848 DGAT1 ARHGAP39 MAF1 SHARPIN ZNF251 CYC1 SLC39A4 MIR939 TMEM249 SLC52A2 LRRC14 FBXL6 PPP1R16A SCX LOC101928953 TONSL-AS1 CPSF1 EXOSC4 RECQL4 MIR6893 GPAA1 MIR7112 VPS28 C8orf82 SMPD5 SCRT1 MIR1234 MIR6849 HSF1 BOP1 WDR97 LOC101928902 HGH1 SPATC1 TONSL MIR6847 CYHR1 KIFC2 MIR6846 MROH1 GPT OPLAH
nsv1025071	Chr.8:144044224 - 144300847 on Build GRCh38	Gain	GPAA1 MIR7112 SMPD5 MAF1 SHARPIN CYC1 HSF1 BOP1 WDR97 SCX HGH1 SPATC1 EXOSC4 MIR6847 MIR6846 MROH1 OPLAH

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

ribosomal protein

Gene Ontology Categories:

Process(es)

cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
rRNA processing
cell proliferation
ribosome biogenesis
regulation of cell cycle

Function(s)

protein binding
ribonucleoprotein complex binding
poly(A) RNA binding