Hs03695061_cn

• Gene Symbol: PPP1R16A
• Assay Reference Genome Location: Chr.8:144495945 on build GRCh38
• Cytoband: 8q24.3

Target Gene Details

• Entrez Gene ID: 84988
• Gene Name: protein phosphatase 1 regulatory subunit 16A
• Gene Aliases: MYPT3
• Location: Chr.8:144477987-144502121 on Build GRCh38
• Assay Gene Location: Within Intron 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PPP1R16A	XM_005272350.2			XP_005272407.1
	XM_017013912.1			XP_016869401.1
	XM_017013913.1			XP_016869402.1
	XM_017013914.1			XP_016869403.1
	XM_017013915.1			XP_016869404.1
	AK090471.1			BAC03452.1
	BM761618.1
	BM762557.1
	CN301973.1
	DB457525.1
	HY013777.1
	HY050499.1
	HY168641.1
	HY176205.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv907n27	Chr.8:144416180 - 144525122 on Build GRCh38	Loss	GPT FOXH1 SLC39A4 MFSD3 TONSL-AS1 MIR6893 VPS28 LRRC24 LOC101928953 PPP1R16A CYHR1 KIFC2 RECQL4 LRRC14 TONSL
nsv470249	Chr.8:143889098 - 144519234 on Build GRCh38	Loss	GPT FOXH1 MFSD3 MIR6847 BOP1 FBXL6 PLEC HGH1 SHARPIN PPP1R16A SMPD5 MAF1 TMEM249 SPATC1 ADCK5 RECQL4 SCRT1 MIR939 LRRC14 OPLAH TONSL SLC52A2 SCX MIR6849 SLC39A4 TONSL-AS1 LOC101928902 GRINA MIR6893 PARP10 CYC1 VPS28 MIR661 GPAA1 CPSF1 LOC101928953 MIR6846 MIR6848 CYHR1 KIFC2 MIR1234 EXOSC4 MROH1 MIR7112 HSF1 WDR97 DGAT1
dgv12434n54	Chr.8:144270080 - 144516801 on Build GRCh38	Loss	GPT FOXH1 MFSD3 BOP1 FBXL6 PPP1R16A TMEM249 ADCK5 RECQL4 SCRT1 MIR939 TONSL SLC52A2 MIR6849 SLC39A4 TONSL-AS1 LOC101928902 MIR6893 VPS28 CPSF1 LOC101928953 MIR6848 CYHR1 KIFC2 MIR1234 HSF1 DGAT1
dgv12442n54	Chr.8:144492696 - 144516381 on Build GRCh38	Loss	GPT LOC101928953 PPP1R16A MFSD3 RECQL4
nsv612951	Chr.8:144479830 - 144677692 on Build GRCh38	Loss	GPT LOC101928953 PPP1R16A ARHGAP39 MFSD3 RECQL4 LRRC14 C8orf82 LRRC24
nsv831489	Chr.8:144342140 - 144544026 on Build GRCh38	Loss	GPT FOXH1 MFSD3 FBXL6 LRRC24 PPP1R16A ARHGAP39 TMEM249 ADCK5 RECQL4 MIR939 LRRC14 TONSL SLC52A2 MIR6849 SLC39A4 TONSL-AS1 LOC101928902 MIR6893 VPS28 CPSF1 LOC101928953 CYHR1 KIFC2 MIR1234 C8orf82
nsv515809	Chr.8:143904439 - 144519234 on Build GRCh38	Gain+Loss	GPT FOXH1 MFSD3 MIR6847 BOP1 FBXL6 PLEC HGH1 SHARPIN PPP1R16A SMPD5 MAF1 TMEM249 SPATC1 ADCK5 RECQL4 SCRT1 MIR939 LRRC14 OPLAH TONSL SLC52A2 SCX MIR6849 SLC39A4 TONSL-AS1 LOC101928902 GRINA MIR6893 PARP10 CYC1 VPS28 MIR661 GPAA1 CPSF1 LOC101928953 MIR6846 MIR6848 CYHR1 KIFC2 MIR1234 EXOSC4 MROH1 MIR7112 HSF1 WDR97 DGAT1
nsv612940	Chr.8:144436292 - 144613673 on Build GRCh38	Loss	GPT FOXH1 MFSD3 TONSL-AS1 LRRC24 LOC101928953 PPP1R16A ARHGAP39 CYHR1 KIFC2 RECQL4 LRRC14 C8orf82 TONSL
dgv12439n54	Chr.8:144438306 - 144525122 on Build GRCh38	Loss	GPT LOC101928953 FOXH1 PPP1R16A MFSD3 TONSL-AS1 CYHR1 KIFC2 RECQL4 LRRC14 TONSL LRRC24
nsv428208	Chr.8:144041826 - 144722291 on Build GRCh38	Gain	GPT FOXH1 MFSD3 MIR6847 BOP1 FBXL6 HGH1 SHARPIN LRRC24 PPP1R16A ARHGAP39 SMPD5 ZNF251 MAF1 TMEM249 SPATC1 ADCK5 RECQL4 SCRT1 MIR939 LRRC14 OPLAH TONSL SLC52A2 SCX MIR6849 SLC39A4 TONSL-AS1 LOC101928902 MIR6893 CYC1 VPS28 GPAA1 CPSF1 LOC101928953 MIR6846 MIR6848 CYHR1 KIFC2 MIR1234 EXOSC4 MROH1 MIR7112 HSF1 WDR97 DGAT1 C8orf82
nsv612955	Chr.8:144494912 - 144502322 on Build GRCh38	Loss	GPT LOC101928953 PPP1R16A
esv29999	Chr.8:144456732 - 144525122 on Build GRCh38	Loss	GPT LOC101928953 FOXH1 PPP1R16A MFSD3 CYHR1 KIFC2 RECQL4 LRRC14 LRRC24

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

phosphatase modulator

Gene Ontology Categories:

Process(es)

regulation of catalytic activity

Function(s)

protein binding
protein phosphatase type 1 regulator activity