Hs03700577_cn

• Gene Symbol: ANAPC2
• Assay Reference Genome Location: Chr.9:137178153 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 29882
• Gene Name: anaphase promoting complex subunit 2
• Gene Aliases: APC2
• Location: Chr.9:137174784-137188605 on Build GRCh38
• Assay Gene Location: Within Intron 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ANAPC2	NM_013366.3			NP_037498.1
	AB037827.1			BAA92644.1
	AF191337.1			AAF05751.1
	AK294601.1
	BC001579.1			AAH01579.1
	BC009487.2			AAH09487.2
	BC032503.1			AAH32503.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv616007	Chr.9:137079368 - 137240666 on Build GRCh38	Loss	ANAPC2 SSNA1 CYSRT1 TMEM203 MIR3621 DPP7 MAN1B1 LRRC26 SLC34A3 GRIN1 NDOR1 TPRN UAP1L1 TMEM210 LOC101930307 RNF224 RNF208 MAN1B1-AS1
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	ANAPC2 SSNA1 CYSRT1 TUBB4B TMEM203 TOR4A SLC34A3 NELFB FAM166A NRARP NDOR1 TPRN STPG3 RNF224 RNF208 EXD3 C9orf173-AS1
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	PRR31 FBXW5 NPDC1 MAN1B1 LRRC26 CCDC183 NDOR1 TPRN LCNL1 MAMDC4 MAN1B1-AS1 LCN12 DPP7 ENTPD8 GRIN1 UAP1L1 CLIC3 STPG3 LOC101930307 RNF208 EXD3 MIR7114 CYSRT1 C9orf139 SAPCD2 NOXA1 PNPLA7 TOR4A MIR3621 C8G NSMF C9orf172 PHPT1 NRARP C9orf142 MIR4292 TMEM210 PTGDS RNF224 RABL6 ANAPC2 SSNA1 TUBB4B TMEM203 MIR4479 ABCA2 TRAF2 CCDC183-AS1 SLC34A3 NELFB FAM166A FUT7 EDF1 ENTPD2 C9orf173-AS1
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	ANAPC2 SSNA1 CYSRT1 TUBB4B TMEM203 TOR4A MIR3621 LRRC26 SLC34A3 GRIN1 NELFB FAM166A NRARP NDOR1 TPRN STPG3 TMEM210 RNF224 RNF208 EXD3 C9orf173-AS1
esv2761561	Chr.9:137030185 - 137191593 on Build GRCh38	Gain	ANAPC2 SSNA1 C9orf139 NPDC1 SAPCD2 MIR3621 DPP7 MAN1B1 LRRC26 GRIN1 UAP1L1 FUT7 TMEM210 LOC101930307 ENTPD2 MAN1B1-AS1
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	ANAPC2 SSNA1 CYSRT1 TUBB4B NOXA1 TMEM203 TOR4A MIR3621 LRRC26 SLC34A3 ENTPD8 GRIN1 NELFB FAM166A NRARP NDOR1 TPRN STPG3 TMEM210 RNF224 RNF208 EXD3 C9orf173-AS1
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	PRR31 AGPAT2 FBXW5 NPDC1 LCN8 MIR126 MAN1B1 LRRC26 CCDC183 NDOR1 TPRN LCNL1 MAMDC4 MAN1B1-AS1 LOC100128593 LCN12 LCN10 DPP7 GRIN1 FAM69B UAP1L1 HSPC324 CLIC3 STPG3 LOC101930307 RNF208 EXD3 CYSRT1 C9orf139 SAPCD2 LCN15 TOR4A MIR3621 TMEM141 C8G C9orf172 PHPT1 SNHG7 LCN6 NRARP C9orf142 MIR4292 MIR6722 TMEM210 PTGDS RNF224 RABL6 ANAPC2 SSNA1 TUBB4B EGFL7 TMEM203 MIR4479 SNORA17B ABCA2 TRAF2 CCDC183-AS1 SLC34A3 NELFB FAM166A SNORA17A FUT7 EDF1 LINC01451 ENTPD2 C9orf173-AS1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

mitotic nuclear division
anaphase-promoting complex-dependent catabolic process
positive regulation of synaptic plasticity
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of axon extension
positive regulation of dendrite morphogenesis
cell division
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
protein K11-linked ubiquitination
positive regulation of synapse maturation

Function(s)

ubiquitin protein ligase binding
ubiquitin protein ligase activity