Hs03700577_cn

• Gene Symbol: ANAPC2
• Assay Reference Genome Location: Chr.9:137178153 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 29882
• Gene Name: anaphase promoting complex subunit 2
• Gene Aliases: APC2
• Location: Chr.9:137174784-137188605 on Build GRCh38
• Assay Gene Location: Within Intron 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ANAPC2	NM_013366.3			NP_037498.1
	AB037827.1			BAA92644.1
	AF191337.1			AAF05751.1
	AK294601.1
	BC001579.1			AAH01579.1
	BC009487.2			AAH09487.2
	BC032503.1			AAH32503.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv616007	Chr.9:137079368 - 137240666 on Build GRCh38	Loss	TMEM210 SLC34A3 RNF224 MIR3621 TMEM203 LOC101930307 RNF208 ANAPC2 CYSRT1 NDOR1 MAN1B1-AS1 MAN1B1 UAP1L1 LRRC26 SSNA1 TPRN GRIN1 DPP7
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	SLC34A3 RNF224 TUBB4B TMEM203 FAM166A RNF208 ANAPC2 CYSRT1 NDOR1 TOR4A EXD3 SSNA1 STPG3 TPRN C9orf173-AS1 NRARP NELFB
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	TMEM210 SLC34A3 LOC101930307 MIR4479 MIR7114 SAPCD2 NDOR1 CCDC183-AS1 FBXW5 LRRC26 ENTPD8 NOXA1 GRIN1 NPDC1 RABL6 LCNL1 NSMF TRAF2 RNF224 MIR3621 ABCA2 FAM166A LCN12 TOR4A MAN1B1 UAP1L1 C9orf172 STPG3 PRR31 MAMDC4 ENTPD2 PTGDS CLIC3 TUBB4B PHPT1 TMEM203 C9orf139 ANAPC2 CYSRT1 EXD3 SSNA1 C9orf142 TPRN MIR4292 C9orf173-AS1 NELFB CCDC183 C8G RNF208 PNPLA7 FUT7 MAN1B1-AS1 NRARP DPP7 EDF1
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	TMEM210 SLC34A3 RNF224 MIR3621 TUBB4B TMEM203 FAM166A RNF208 ANAPC2 CYSRT1 NDOR1 TOR4A LRRC26 EXD3 SSNA1 STPG3 TPRN GRIN1 C9orf173-AS1 NRARP NELFB
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	TMEM210 SLC34A3 RNF224 MIR3621 TUBB4B TMEM203 FAM166A RNF208 ANAPC2 CYSRT1 NDOR1 TOR4A LRRC26 ENTPD8 EXD3 SSNA1 STPG3 NOXA1 TPRN GRIN1 C9orf173-AS1 NRARP NELFB
esv2761561	Chr.9:137030185 - 137191593 on Build GRCh38	Gain	TMEM210 MIR3621 LOC101930307 C9orf139 ANAPC2 SAPCD2 FUT7 MAN1B1-AS1 MAN1B1 UAP1L1 LRRC26 SSNA1 GRIN1 NPDC1 ENTPD2 DPP7
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	TMEM210 SLC34A3 LOC101930307 MIR4479 LCN6 SAPCD2 NDOR1 CCDC183-AS1 FBXW5 LRRC26 FAM69B GRIN1 SNHG7 NPDC1 RABL6 LCNL1 EGFL7 TRAF2 RNF224 MIR3621 ABCA2 HSPC324 FAM166A SNORA17B LCN12 TOR4A MAN1B1 UAP1L1 C9orf172 STPG3 AGPAT2 PRR31 MAMDC4 LINC01451 ENTPD2 LCN8 PTGDS CLIC3 SNORA17A TUBB4B PHPT1 TMEM203 C9orf139 ANAPC2 CYSRT1 MIR6722 MIR126 EXD3 SSNA1 C9orf142 TPRN MIR4292 C9orf173-AS1 NELFB CCDC183 LCN10 C8G RNF208 LOC100128593 LCN15 FUT7 TMEM141 MAN1B1-AS1 NRARP DPP7 EDF1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

mitotic nuclear division
anaphase-promoting complex-dependent catabolic process
positive regulation of synaptic plasticity
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of axon extension
positive regulation of dendrite morphogenesis
cell division
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
protein K11-linked ubiquitination
positive regulation of synapse maturation

Function(s)

ubiquitin protein ligase binding
ubiquitin protein ligase activity