Hs03706761_cn

• Gene Symbol: EXD3
• Assay Reference Genome Location: Chr.9:137346362 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 54932
• Gene Name: exonuclease 3'-5' domain containing 3
• Gene Aliases: mut-7
• Location: Chr.9:137306894-137423262 on Build GRCh38
• Assay Gene Location: Within Intron 27

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
EXD3	NM_017820.4			NP_060290.3
	XM_011518810.1			XP_011517112.1
	XM_011518814.1			XP_011517116.1
	XM_011518815.1			XP_011517117.1
	XM_017014861.1			XP_016870350.1
	XM_017014862.1			XP_016870351.1
	XM_017014863.1			XP_016870352.1
	XM_017014864.1			XP_016870353.1
	XM_017014865.1			XP_016870354.1
	XM_017014866.1			XP_016870355.1
	XM_017014867.1			XP_016870356.1
	AB061798.1			BAC10986.1
	AK055004.1			BAB70838.1
	AK091390.1
	AK094438.1			BAC04356.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv33008	Chr.9:137336337 - 137346333 on Build GRCh38	Loss	EXD3
dgv2190e212	Chr.9:137339864 - 137372892 on Build GRCh38	Gain	EXD3
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	C9orf172 RNF208 ABCA2 MIR3621 TPRN CCDC183-AS1 C9orf173-AS1 TOR4A PRR31 ANAPC2 NOXA1 CLIC3 MAN1B1 MAN1B1-AS1 C8G SSNA1 FAM166A TUBB4B MIR4479 EDF1 UAP1L1 LCN12 TMEM203 EXD3 TRAF2 NELFB RNF224 LRRC26 NDOR1 MIR7114 CYSRT1 NRARP NPDC1 PNPLA7 FUT7 CCDC183 RABL6 FBXW5 STPG3 PHPT1 LOC101930307 DPP7 NSMF SAPCD2 SLC34A3 PTGDS C9orf139 GRIN1 MAMDC4 MIR4292 C9orf142 ENTPD8 LCNL1 ENTPD2 TMEM210
esv2759721	Chr.9:137303332 - 137447299 on Build GRCh38	Loss	EXD3 ENTPD8 NOXA1
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	SSNA1 CYSRT1 FAM166A NRARP TUBB4B SLC34A3 TMEM203 RNF208 MIR3621 TPRN EXD3 NELFB C9orf173-AS1 GRIN1 RNF224 TOR4A LRRC26 STPG3 NDOR1 ANAPC2 TMEM210
nsv1043075	Chr.9:137333691 - 137361369 on Build GRCh38	Gain+Loss	EXD3
nsv6770	Chr.9:137316337 - 137347440 on Build GRCh38	Insertion	EXD3
nsv1050826	Chr.9:137325391 - 137378611 on Build GRCh38	Gain	EXD3
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	SSNA1 CYSRT1 FAM166A NRARP TUBB4B SLC34A3 TMEM203 RNF208 MIR3621 TPRN EXD3 NELFB C9orf173-AS1 GRIN1 RNF224 TOR4A LRRC26 STPG3 ENTPD8 NDOR1 ANAPC2 NOXA1 TMEM210
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	C9orf172 RNF208 ABCA2 MIR126 MIR3621 TPRN CCDC183-AS1 C9orf173-AS1 TOR4A FAM69B MIR6722 PRR31 HSPC324 ANAPC2 CLIC3 MAN1B1 MAN1B1-AS1 C8G SSNA1 FAM166A TMEM141 TUBB4B MIR4479 EDF1 UAP1L1 LCN12 TMEM203 AGPAT2 EXD3 TRAF2 NELFB RNF224 LRRC26 SNHG7 NDOR1 SNORA17B LCN10 LCN8 LCN15 CYSRT1 NRARP LOC100128593 NPDC1 SNORA17A FUT7 CCDC183 RABL6 FBXW5 STPG3 PHPT1 LOC101930307 DPP7 SAPCD2 EGFL7 SLC34A3 PTGDS C9orf139 LINC01451 GRIN1 MAMDC4 LCN6 MIR4292 C9orf142 LCNL1 ENTPD2 TMEM210
nsv1037407	Chr.9:137275904 - 137361369 on Build GRCh38	Gain	EXD3 NRARP TOR4A

More Information

Additional Information:

For this assay, SNP(s) [rs146285957,rs75046225] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

nucleic acid phosphodiester bond hydrolysis

Function(s)

nucleic acid binding
3'-5' exonuclease activity
metal ion binding