Hs03706761_cn

• Gene Symbol: EXD3
• Assay Reference Genome Location: Chr.9:137346362 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 54932
• Gene Name: exonuclease 3'-5' domain containing 3
• Gene Aliases: mut-7
• Location: Chr.9:137306894-137423262 on Build GRCh38
• Assay Gene Location: Within Intron 27

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
EXD3	NM_017820.4			NP_060290.3
	XM_011518810.1			XP_011517112.1
	XM_011518814.1			XP_011517116.1
	XM_011518815.1			XP_011517117.1
	XM_017014861.1			XP_016870350.1
	XM_017014862.1			XP_016870351.1
	XM_017014863.1			XP_016870352.1
	XM_017014864.1			XP_016870353.1
	XM_017014865.1			XP_016870354.1
	XM_017014866.1			XP_016870355.1
	XM_017014867.1			XP_016870356.1
	AB061798.1			BAC10986.1
	AK055004.1			BAB70838.1
	AK091390.1
	AK094438.1			BAC04356.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv2190e212	Chr.9:137339864 - 137372892 on Build GRCh38	Gain	EXD3
esv33008	Chr.9:137336337 - 137346333 on Build GRCh38	Loss	EXD3
esv2759721	Chr.9:137303332 - 137447299 on Build GRCh38	Loss	ENTPD8 EXD3 NOXA1
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	TUBB4B MIR4292 FAM166A PNPLA7 ENTPD8 TOR4A SSNA1 NDOR1 TRAF2 CCDC183 NELFB FBXW5 CLIC3 LCNL1 LCN12 PHPT1 LOC101930307 RABL6 ENTPD2 MAN1B1-AS1 CCDC183-AS1 RNF208 DPP7 C9orf172 NSMF MAMDC4 NRARP CYSRT1 PTGDS C8G ABCA2 NPDC1 UAP1L1 C9orf139 LRRC26 PRR31 MIR4479 C9orf173-AS1 TMEM203 MAN1B1 GRIN1 SAPCD2 FUT7 TPRN SLC34A3 MIR7114 C9orf142 EDF1 EXD3 STPG3 NOXA1 TMEM210 RNF224 ANAPC2 MIR3621
nsv1043075	Chr.9:137333691 - 137361369 on Build GRCh38	Gain+Loss	EXD3
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	TUBB4B NRARP FAM166A CYSRT1 TPRN SLC34A3 TOR4A SSNA1 EXD3 STPG3 NDOR1 TMEM210 LRRC26 RNF208 RNF224 C9orf173-AS1 TMEM203 ANAPC2 NELFB GRIN1 MIR3621
nsv6770	Chr.9:137316337 - 137347440 on Build GRCh38	Insertion	EXD3
nsv1050678	Chr.9:137325391 - 137361369 on Build GRCh38	Gain	EXD3
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	TUBB4B NRARP FAM166A CYSRT1 TPRN SLC34A3 ENTPD8 TOR4A SSNA1 EXD3 STPG3 NDOR1 NOXA1 TMEM210 LRRC26 RNF208 RNF224 C9orf173-AS1 TMEM203 ANAPC2 NELFB GRIN1 MIR3621
nsv1037407	Chr.9:137275904 - 137361369 on Build GRCh38	Gain	NRARP TOR4A EXD3
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	LCN10 TUBB4B MIR4292 FAM166A TMEM141 FAM69B TOR4A SSNA1 LINC01451 NDOR1 TRAF2 HSPC324 CCDC183 NELFB FBXW5 CLIC3 LCNL1 LCN12 PHPT1 LOC101930307 RABL6 ENTPD2 MAN1B1-AS1 SNORA17B CCDC183-AS1 LCN6 LCN15 RNF208 DPP7 SNORA17A C9orf172 MAMDC4 NRARP CYSRT1 PTGDS C8G ABCA2 LOC100128593 NPDC1 EGFL7 MIR6722 UAP1L1 C9orf139 LRRC26 PRR31 MIR4479 MIR126 C9orf173-AS1 TMEM203 MAN1B1 GRIN1 SAPCD2 FUT7 TPRN SLC34A3 C9orf142 EDF1 EXD3 STPG3 LCN8 TMEM210 RNF224 SNHG7 ANAPC2 AGPAT2 MIR3621

More Information

Additional Information:

For this assay, SNP(s) [rs146285957,rs75046225] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

nucleic acid phosphodiester bond hydrolysis

Function(s)

nucleic acid binding
3'-5' exonuclease activity
metal ion binding