Hs03715377_cn

• Gene Symbol: NDOR1
• Assay Reference Genome Location: Chr.9:137218084 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 27158
• Gene Name: NADPH dependent diflavin oxidoreductase 1
• Gene Aliases: NR1, bA350O14.9
• Location: Chr.9:137205667-137219361 on Build GRCh38
• Assay Gene Location: Within Exon 13

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NDOR1	NM_001144026.2	14	3600	NP_001137498.1
	NM_001144027.2	13	3449	NP_001137499.1
	NM_001144028.2	14	3552	NP_001137500.1
	NM_014434.3	14	3573	NP_055249.1
	XM_011518545.1	13	3488	XP_011516847.1
	XM_011518547.1	14	3390	XP_011516849.1
	XM_011518548.2	13	4790	XP_011516850.1
	XM_017014627.1	14	3551	XP_016870116.1
	AL133632.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv13010n54	Chr.9:137191539 - 137233413 on Build GRCh38	Loss	RNF208 SLC34A3 CYSRT1 NDOR1 TMEM203 RNF224 TPRN
nsv616012	Chr.9:137197680 - 137223834 on Build GRCh38	Loss	RNF208 NDOR1 TMEM203 TPRN
nsv616007	Chr.9:137079368 - 137240666 on Build GRCh38	Loss	MAN1B1-AS1 ANAPC2 SSNA1 GRIN1 MIR3621 TMEM203 MAN1B1 LOC101930307 TPRN RNF208 TMEM210 DPP7 SLC34A3 CYSRT1 NDOR1 LRRC26 RNF224 UAP1L1
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	FAM166A ANAPC2 TUBB4B SSNA1 NELFB TMEM203 NRARP TPRN RNF208 C9orf173-AS1 EXD3 TOR4A SLC34A3 CYSRT1 NDOR1 STPG3 RNF224
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	MAMDC4 FAM166A C9orf172 TMEM203 RNF208 TMEM210 C9orf173-AS1 PTGDS TOR4A EDF1 SLC34A3 NDOR1 ABCA2 FUT7 C8G C9orf139 ANAPC2 GRIN1 MIR3621 NPDC1 TRAF2 FBXW5 LRRC26 LCNL1 SSNA1 ENTPD8 MAN1B1 NRARP RABL6 PNPLA7 EXD3 DPP7 MIR4479 CLIC3 STPG3 RNF224 PHPT1 MAN1B1-AS1 LCN12 MIR7114 PRR31 MIR4292 TUBB4B SAPCD2 NELFB LOC101930307 ENTPD2 CCDC183 TPRN C9orf142 NOXA1 NSMF CYSRT1 CCDC183-AS1 UAP1L1
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	FAM166A ANAPC2 TUBB4B SSNA1 NELFB GRIN1 MIR3621 TMEM203 NRARP TPRN RNF208 TMEM210 C9orf173-AS1 EXD3 TOR4A SLC34A3 CYSRT1 NDOR1 LRRC26 STPG3 RNF224
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	FAM166A ANAPC2 TUBB4B SSNA1 ENTPD8 NELFB GRIN1 MIR3621 TMEM203 NRARP TPRN RNF208 TMEM210 C9orf173-AS1 EXD3 TOR4A NOXA1 SLC34A3 CYSRT1 NDOR1 LRRC26 STPG3 RNF224
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	LOC100128593 SNORA17B MAMDC4 FAM166A TMEM141 C9orf172 TMEM203 LCN6 RNF208 TMEM210 C9orf173-AS1 PTGDS TOR4A EDF1 SLC34A3 NDOR1 ABCA2 SNHG7 FUT7 C8G LCN10 C9orf139 ANAPC2 GRIN1 MIR3621 EGFL7 NPDC1 TRAF2 FBXW5 LRRC26 LCNL1 SNORA17A SSNA1 LINC01451 MAN1B1 NRARP RABL6 EXD3 LCN15 DPP7 MIR4479 CLIC3 STPG3 RNF224 MIR126 PHPT1 MAN1B1-AS1 LCN12 PRR31 MIR6722 MIR4292 TUBB4B SAPCD2 NELFB HSPC324 FAM69B LOC101930307 AGPAT2 ENTPD2 CCDC183 TPRN C9orf142 CYSRT1 LCN8 CCDC183-AS1 UAP1L1

More Information

Additional Information:

For this assay, SNP(s) [rs116151678] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

oxidoreductase

Gene Ontology Categories:

Process(es)

cell death
iron-sulfur cluster assembly
cellular response to menadione
oxidation-reduction process

Function(s)

NADPH-hemoprotein reductase activity
protein binding
FMN binding
oxidoreductase activity
flavin adenine dinucleotide binding
NADP binding