Hs03769961_cn

• Gene Symbol: PIDD1
• Assay Reference Genome Location: Chr.11:809105 on build GRCh38
• Cytoband: 11p15.5

Target Gene Details

• Entrez Gene ID: 55367
• Gene Name: p53-induced death domain protein 1
• Gene Aliases: LRDD, PIDD
• Location: Chr.11:799179-809504 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PIDD1	XM_005253005.4			XP_005253062.1
	XM_005253006.4			XP_005253063.1
	XM_005253007.3			XP_005253064.1
	XM_005253008.4			XP_005253065.1
	XM_011520209.2	1	150	XP_011518511.1
	XM_011520210.2			XP_011518512.1
	XM_011520211.2			XP_011518513.1
	XM_011520212.1			XP_011518514.1
	AB208832.1			BAD92069.1
	BG723687.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv552871	Chr.11:766479 - 870446 on Build GRCh38	Loss	CD151 CRACR2B SLC25A22 CHID1 PIDD1 POLR2L RPLP2 TSPAN4 SNORA52 PANO1 PNPLA2 LOC171391 CEND1 PDDC1
nsv469923	Chr.11:378188 - 1302334 on Build GRCh38	Loss	AP2A2 IRF7 TALDO1 CD151 SLC25A22 LOC143666 LOC101927503 DEAF1 PIDD1 SCT HRAS POLR2L RNH1 TOLLIP RPLP2 PKP3 MIR210HG SNORA52 TMEM80 PHRF1 MUC5AC MUC2 LRRC56 SIGIRR RASSF7 MUC6 PNPLA2 CDHR5 ANO9 CRACR2B DRD4 LMNTD2 CHID1 LOC101059906 PTDSS2 EPS8L2 MIR210 TSPAN4 PANO1 MUC5B B4GALNT4 LOC171391 MIR6744 CEND1 PDDC1
dgv1013n100	Chr.11:772982 - 933569 on Build GRCh38	Gain	AP2A2 CD151 CRACR2B SLC25A22 CHID1 PIDD1 POLR2L RPLP2 TSPAN4 SNORA52 PANO1 PNPLA2 LOC171391 CEND1 PDDC1
esv2759794	Chr.11:409846 - 1336162 on Build GRCh38	Loss	AP2A2 IRF7 TALDO1 CD151 SLC25A22 LOC143666 LOC101927503 DEAF1 PIDD1 SCT HRAS POLR2L RNH1 TOLLIP RPLP2 MIR210HG SNORA52 TMEM80 PHRF1 MUC5AC MUC2 LRRC56 SIGIRR RASSF7 MUC6 PNPLA2 CDHR5 ANO9 CRACR2B DRD4 LMNTD2 CHID1 LOC101059906 PTDSS2 EPS8L2 MIR210 TSPAN4 PANO1 MUC5B LOC171391 MIR6744 CEND1 TOLLIP-AS1 PDDC1
nsv832044	Chr.11:809019 - 938308 on Build GRCh38	Loss	AP2A2 TSPAN4 CD151 CRACR2B SNORA52 CHID1 PIDD1 POLR2L PNPLA2 RPLP2
dgv182e199	Chr.11:349830 - 943372 on Build GRCh38	Deletion	AP2A2 IRF7 TALDO1 CD151 SLC25A22 LOC143666 DEAF1 PIDD1 SCT HRAS POLR2L RNH1 RPLP2 PKP3 MIR210HG SNORA52 TMEM80 PHRF1 LRRC56 SIGIRR RASSF7 PNPLA2 CDHR5 ANO9 CRACR2B DRD4 LMNTD2 CHID1 LOC101059906 PTDSS2 EPS8L2 MIR210 TSPAN4 PANO1 B4GALNT4 LOC171391 CEND1 PDDC1
nsv552870	Chr.11:743813 - 810882 on Build GRCh38	Loss	TALDO1 SLC25A22 PANO1 PIDD1 LOC171391 CEND1 PDDC1 RPLP2
nsv1040044	Chr.11:776335 - 900929 on Build GRCh38	Gain+Loss	CD151 CRACR2B SLC25A22 CHID1 PIDD1 POLR2L RPLP2 TSPAN4 SNORA52 PANO1 PNPLA2 LOC171391 CEND1 PDDC1
nsv8759	Chr.11:775539 - 835248 on Build GRCh38	Gain	CD151 CRACR2B SLC25A22 SNORA52 PANO1 PIDD1 PNPLA2 LOC171391 CEND1 PDDC1 RPLP2
nsv1159791	Chr.11:461793 - 909492 on Build GRCh38	Deletion	IRF7 TALDO1 CD151 SLC25A22 LOC143666 DEAF1 PIDD1 SCT HRAS POLR2L RNH1 RPLP2 MIR210HG SNORA52 TMEM80 PHRF1 LRRC56 RASSF7 PNPLA2 CDHR5 CRACR2B DRD4 LMNTD2 CHID1 LOC101059906 PTDSS2 EPS8L2 MIR210 TSPAN4 PANO1 LOC171391 CEND1 PDDC1
nsv951272	Chr.11:751201 - 911500 on Build GRCh38	Deletion	TALDO1 CD151 CRACR2B SLC25A22 CHID1 PIDD1 POLR2L RPLP2 TSPAN4 SNORA52 PANO1 PNPLA2 LOC171391 CEND1 PDDC1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
cellular response to DNA damage stimulus
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
signal transduction
regulation of apoptotic process
positive regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of NF-kappaB transcription factor activity
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors

Function(s)

death receptor binding
protein binding