Hs03774792_cn

• Gene Symbol: LMNTD2
• Assay Reference Genome Location: Chr.11:560122 on build GRCh38
• Cytoband: 11p15.5

Target Gene Details

• Entrez Gene ID: 256329
• Gene Name: lamin tail domain containing 2
• Gene Aliases: C11orf35
• Location: Chr.11:554850-560780 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LMNTD2	NM_173573.2			NP_775844.2
	XM_017017478.1			XP_016872967.1
	BC039077.1			AAH39077.1
	BX384085.2

Target Gene Details

• Entrez Gene ID: 8045
• Gene Name: Ras association domain family member 7
• Gene Aliases: C11orf13, HRAS1, HRC1
• Location: Chr.11:559776-564025 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
RASSF7	XM_005253149.3			XP_005253206.2
	XM_011520389.1			XP_011518691.1
	XM_017018360.1			XP_016873849.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv552854	Chr.11:511805 - 619789 on Build GRCh38	Loss	LMNTD2 IRF7 LOC101059906 PHRF1 MIR210 LOC143666 RASSF7 HRAS MIR210HG CDHR5 LRRC56
dgv1523n54	Chr.11:557342 - 656940 on Build GRCh38	Gain	LMNTD2 IRF7 DRD4 SCT PHRF1 MIR210 LOC143666 RASSF7 MIR210HG DEAF1 CDHR5
nsv527327	Chr.11:295343 - 620599 on Build GRCh38	Loss	IFITM2 IFITM5 LMNTD2 LOC101059906 MIR210 RASSF7 PGGHG ANO9 CDHR5 B4GALNT4 SIGIRR IRF7 PHRF1 LOC143666 IFITM3 PTDSS2 HRAS RNH1 IFITM1 PKP3 MIR210HG LRRC56
nsv951270	Chr.11:528401 - 628100 on Build GRCh38	Deletion	LMNTD2 IRF7 LOC101059906 SCT PHRF1 MIR210 LOC143666 RASSF7 HRAS MIR210HG CDHR5 LRRC56
nsv469923	Chr.11:378188 - 1302334 on Build GRCh38	Loss	LMNTD2 LOC171391 PNPLA2 LOC101059906 AP2A2 B4GALNT4 TOLLIP POLR2L CEND1 CD151 MUC2 PTDSS2 RNH1 TALDO1 DEAF1 CRACR2B CHID1 MUC5B DRD4 MUC5AC RPLP2 SCT MIR210 RASSF7 TSPAN4 ANO9 CDHR5 SIGIRR PIDD1 IRF7 MUC6 LOC101927503 PHRF1 EPS8L2 LOC143666 PDDC1 SLC25A22 HRAS TMEM80 SNORA52 PKP3 MIR210HG PANO1 LRRC56 MIR6744
esv2759794	Chr.11:409846 - 1336162 on Build GRCh38	Loss	LMNTD2 LOC171391 PNPLA2 LOC101059906 TOLLIP-AS1 AP2A2 TOLLIP POLR2L CEND1 CD151 MUC2 PTDSS2 RNH1 TALDO1 DEAF1 CRACR2B CHID1 MUC5B DRD4 MUC5AC RPLP2 SCT MIR210 RASSF7 TSPAN4 ANO9 CDHR5 SIGIRR PIDD1 IRF7 MUC6 LOC101927503 PHRF1 EPS8L2 LOC143666 PDDC1 SLC25A22 HRAS TMEM80 SNORA52 MIR210HG PANO1 LRRC56 MIR6744
nsv1039558	Chr.11:534242 - 672091 on Build GRCh38	Gain	LMNTD2 DRD4 SCT MIR210 RASSF7 CDHR5 IRF7 PHRF1 LOC143666 HRAS MIR210HG DEAF1 LRRC56
nsv528415	Chr.11:558884 - 620599 on Build GRCh38	Loss	LMNTD2 IRF7 PHRF1 MIR210 LOC143666 RASSF7 MIR210HG CDHR5
dgv182e199	Chr.11:349830 - 943372 on Build GRCh38	Deletion	LMNTD2 LOC171391 PNPLA2 LOC101059906 AP2A2 B4GALNT4 POLR2L CEND1 CD151 PTDSS2 RNH1 TALDO1 DEAF1 CRACR2B CHID1 DRD4 RPLP2 SCT MIR210 RASSF7 TSPAN4 ANO9 CDHR5 SIGIRR PIDD1 IRF7 PHRF1 EPS8L2 LOC143666 PDDC1 SLC25A22 HRAS TMEM80 SNORA52 PKP3 MIR210HG PANO1 LRRC56
nsv1053964	Chr.11:491334 - 692433 on Build GRCh38	Gain	LMNTD2 DRD4 LOC101059906 SCT MIR210 RASSF7 CDHR5 IRF7 PHRF1 LOC143666 PTDSS2 HRAS RNH1 MIR210HG DEAF1 LRRC56
nsv1159791	Chr.11:461793 - 909492 on Build GRCh38	Deletion	LMNTD2 LOC171391 PNPLA2 LOC101059906 POLR2L CEND1 CD151 PTDSS2 RNH1 TALDO1 DEAF1 CRACR2B CHID1 DRD4 RPLP2 SCT MIR210 RASSF7 TSPAN4 CDHR5 PIDD1 IRF7 PHRF1 EPS8L2 LOC143666 PDDC1 SLC25A22 HRAS TMEM80 SNORA52 MIR210HG PANO1 LRRC56
nsv469924	Chr.11:549119 - 609887 on Build GRCh38	Gain	LMNTD2 PHRF1 MIR210 LOC143666 RASSF7 MIR210HG LRRC56

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

positive regulation of mRNA splicing, via spliceosome
apoptotic process
signal transduction
regulation of microtubule cytoskeleton organization

Function(s)

protein binding