Hs03782869_cn

• Gene Symbol: AP2A2
• Assay Reference Genome Location: Chr.11:945198 on build GRCh38
• Cytoband: 11p15.5

Target Gene Details

• Entrez Gene ID: 161
• Gene Name: adaptor related protein complex 2 alpha 2 subunit
• Gene Aliases: ADTAB, CLAPA2, HIP-9, HIP9, HYPJ
• Location: Chr.11:925809-1012245 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
AP2A2	NM_001242837.1			NP_001229766.1
	NM_012305.3			NP_036437.1
	XM_011519929.1			XP_011518231.1
	XM_011519930.2			XP_011518232.1
	AB020706.2			BAA74922.2
	AK001986.1
	AK027891.1			BAB55435.1
	AK223558.1			BAD97278.1
	AK293763.1
	AK299364.1
	BC006155.1			AAH06155.1
	BG705558.1
	BI462785.1
	DB461570.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3625088	Chr.11:876861 - 979340 on Build GRCh38	Gain	CHID1 AP2A2
nsv469923	Chr.11:378188 - 1302334 on Build GRCh38	Loss	RASSF7 LOC101927503 PIDD1 B4GALNT4 TSPAN4 TMEM80 DEAF1 MIR210HG PNPLA2 PKP3 CEND1 MUC5AC LOC101059906 LOC171391 POLR2L MUC2 SIGIRR CD151 ANO9 CHID1 CDHR5 AP2A2 SCT MIR210 DRD4 EPS8L2 TOLLIP PDDC1 TALDO1 SNORA52 LRRC56 CRACR2B PTDSS2 LMNTD2 RNH1 IRF7 HRAS LOC143666 PHRF1 PANO1 MUC5B SLC25A22 RPLP2 MUC6 MIR6744
dgv175e214	Chr.11:851409 - 1043855 on Build GRCh38	Gain	CHID1 TSPAN4 AP2A2 MUC6
nsv428244	Chr.11:882364 - 1061595 on Build GRCh38	Loss	LOC101927503 CHID1 AP2A2 MUC6
esv2759794	Chr.11:409846 - 1336162 on Build GRCh38	Loss	RASSF7 LOC101927503 PIDD1 TSPAN4 TMEM80 DEAF1 MIR210HG PNPLA2 CEND1 MUC5AC LOC101059906 LOC171391 POLR2L MUC2 SIGIRR CD151 ANO9 CHID1 CDHR5 AP2A2 SCT MIR210 DRD4 EPS8L2 TOLLIP PDDC1 TALDO1 SNORA52 LRRC56 CRACR2B TOLLIP-AS1 PTDSS2 LMNTD2 RNH1 IRF7 HRAS LOC143666 PHRF1 PANO1 MUC5B SLC25A22 RPLP2 MUC6 MIR6744
esv2669189	Chr.11:864834 - 1489637 on Build GRCh38	Deletion	LOC101927503 CHID1 BRSK2 TSPAN4 AP2A2 TOLLIP MOB2 TOLLIP-AS1 MUC5AC MUC5B MUC6 MUC2 MIR6744
esv2743878	Chr.11:864732 - 1489652 on Build GRCh38	Deletion	LOC101927503 CHID1 BRSK2 TSPAN4 AP2A2 TOLLIP MOB2 TOLLIP-AS1 MUC5AC MUC5B MUC6 MUC2 MIR6744

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

membrane traffic protein

Gene Ontology Categories:

Process(es)

intracellular protein transport
microtubule-based movement
antigen processing and presentation of exogenous peptide antigen via MHC class II
negative regulation of epidermal growth factor receptor signaling pathway
ephrin receptor signaling pathway
regulation of defense response to virus by virus
Wnt signaling pathway, planar cell polarity pathway
clathrin-mediated endocytosis

Function(s)

molecular_function
protein binding
lipid binding
protein transporter activity
protein kinase binding
protein complex binding
clathrin adaptor activity