Hs03797130_cn

• Gene Symbol: MIR4691
• Assay Reference Genome Location: Chr.11:68033866 on build GRCh38
• Cytoband: 11q13.2

Target Gene Details

• Entrez Gene ID: 100616403
• Gene Name: microRNA 4691
• Gene Aliases: mir-4691
• Location: Chr.11:68033897-68033981 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MIR4691	NR_039840.1

Target Gene Details

• Entrez Gene ID: 4728
• Gene Name: NADH:ubiquinone oxidoreductase core subunit S8
• Gene Aliases: CI-23k, CI23KD, TYKY
• Location: Chr.11:68030617-68036647 on Build GRCh38
• Assay Gene Location: Within Intron 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NDUFS8	NM_002496.3			NP_002487.1
	XM_005274013.1			XP_005274070.1
	XM_005274014.2			XP_005274071.1
	XM_011545053.2			XP_011543355.1
	AK002110.1	3	1660
	AK223114.1			BAD96834.1
	AK314546.1
	BC119753.1
	BC119754.2
	DB498707.1
	U65579.1			AAB51776.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv8836	Chr.11:67985408 - 68052332 on Build GRCh38	Gain	UNC93B1 MIR7113 ALDH3B1 MIR6753 MIR4691 TCIRG1 NDUFS8
dgv1981n54	Chr.11:67579272 - 68049469 on Build GRCh38	Gain	UNC93B1 LOC105369360 FAM86C2P TBX10 DOC2GP NDUFV1 ALDH3B2 ACY3 MIR7113 ALDH3B1 NUDT8 MIR6753 MIR4691 C11orf72 TCIRG1 GSTP1 NDUFS8
nsv825963	Chr.11:67996205 - 68429586 on Build GRCh38	Gain	UNC93B1 LRP5 CHKA MIR7113 C11orf24 ALDH3B1 KMT5B MIR6753 MIR4691 TCIRG1 NDUFS8
nsv555282	Chr.11:68031100 - 68050858 on Build GRCh38	Loss	MIR7113 MIR6753 MIR4691 TCIRG1 NDUFS8
dgv1983n54	Chr.11:68022085 - 68053569 on Build GRCh38	Loss	CHKA MIR7113 ALDH3B1 MIR6753 MIR4691 TCIRG1 NDUFS8
esv2759835	Chr.11:67705434 - 68123822 on Build GRCh38	Gain+Loss	UNC93B1 CHKA MIR7113 ALDH3B1 MIR6753 LOC105369360 MIR4691 FAM86C2P TCIRG1 NDUFS8
nsv951026	Chr.11:67994030 - 68053133 on Build GRCh38	Deletion	UNC93B1 CHKA MIR7113 ALDH3B1 MIR6753 MIR4691 TCIRG1 NDUFS8
nsv469964	Chr.11:67997585 - 68053569 on Build GRCh38	Loss	UNC93B1 CHKA MIR7113 ALDH3B1 MIR6753 MIR4691 TCIRG1 NDUFS8
nsv468606	Chr.11:67585218 - 68049469 on Build GRCh38	Gain	UNC93B1 LOC105369360 FAM86C2P TBX10 DOC2GP NDUFV1 ALDH3B2 ACY3 MIR7113 ALDH3B1 NUDT8 MIR6753 MIR4691 C11orf72 TCIRG1 GSTP1 NDUFS8
dgv1221n100	Chr.11:67979689 - 68054143 on Build GRCh38	Gain	UNC93B1 CHKA MIR7113 ALDH3B1 MIR6753 MIR4691 TCIRG1 NDUFS8
nsv469856	Chr.11:67871566 - 68092023 on Build GRCh38	Gain	UNC93B1 CHKA MIR7113 ALDH3B1 MIR6753 LOC105369360 MIR4691 TCIRG1 NDUFS8

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

oxidoreductase

Gene Ontology Categories:

Process(es)

mitochondrial electron transport, NADH to ubiquinone
response to oxidative stress
mitochondrial respiratory chain complex I assembly

Function(s)

NADH dehydrogenase activity
NADH dehydrogenase (ubiquinone) activity
metal ion binding
4 iron, 4 sulfur cluster binding