Hs03823321_cn

• Gene Symbol: APOBEC1
• Assay Reference Genome Location: Chr.12:7653915 on build GRCh38
• Cytoband: 12p13.31

Target Gene Details

• Entrez Gene ID: 339
• Gene Name: apolipoprotein B mRNA editing enzyme catalytic subunit 1
• Gene Aliases: APOBEC-1, BEDP, CDAR1, HEPR
• Location: Chr.12:7649400-7670599 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
APOBEC1	NM_001304566.1			NP_001291495.1
	NM_001644.4			NP_001635.2
	NM_005889.3			NP_005880.2
	BC096158.1			AAH96158.1
	BC101972.1			AAI01973.1
	BC101973.1			AAI01974.1
	L25877.1			AAA86766.1
	L26234.1			AAA64230.1
	U72890.1			AAD09567.1
	U72891.1			AAD00185.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv1350n100	Chr.12:7502541 - 7672399 on Build GRCh38	Loss	CD163 APOBEC1
nsv826213	Chr.12:7578336 - 7678048 on Build GRCh38	Gain	APOBEC1
nsv1036408	Chr.12:7630029 - 7659414 on Build GRCh38	Loss	APOBEC1
esv3580096	Chr.12:7646240 - 7654203 on Build GRCh38	Loss	APOBEC1
nsv557273	Chr.12:7621432 - 7731755 on Build GRCh38	Loss	CLEC4C GDF3 APOBEC1 DPPA3
nsv826216	Chr.12:7615958 - 7665910 on Build GRCh38	Gain	APOBEC1
dgv5e196	Chr.12:7621924 - 7954221 on Build GRCh38	Duplication	CLEC4C SLC2A14 NANOGNB NANOG GDF3 APOBEC1 DPPA3 NANOGP1 SLC2A3
nsv521149	Chr.12:7604110 - 7684392 on Build GRCh38	Loss	APOBEC1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA processing factor

Gene Ontology Categories:

Process(es)

RNA processing
mRNA processing
lipid metabolic process
response to osmotic stress
cytidine deamination
response to zinc ion
response to gamma radiation
cytidine to uridine editing
mRNA modification
cellular response to insulin stimulus
regulation of cell proliferation
lipoprotein biosynthetic process
response to drug
lipoprotein transport
positive regulation of catalytic activity
response to ethanol
mRNA stabilization
response to calcium ion
defense response to virus
DNA cytosine deamination
DNA demethylation
negative regulation of methylation-dependent chromatin silencing
positive regulation of mRNA modification

Function(s)

RNA binding
mRNA binding
cytidine deaminase activity
cytosine deaminase activity
protein binding
enzyme activator activity
zinc ion binding
AU-rich element binding
protein domain specific binding
ribonucleoprotein complex binding