Hs03846932_cn

• Gene Symbol: GAS6
• Assay Reference Genome Location: Chr.13:113837210 on build GRCh38
• Cytoband: 13q34

Target Gene Details

• Entrez Gene ID: 2621
• Gene Name: growth arrest specific 6
• Gene Aliases: AXLLG, AXSF
• Location: Chr.13:113820549-113864103 on Build GRCh38
• Assay Gene Location: Within Intron 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GAS6	NM_000820.3			NP_000811.1
	AK126533.1			BAC86580.1
	AK290803.1
	AK303145.1
	BC038984.1			AAH38984.1
	BX380508.2
	L13720.1			AAA58494.1

Target Gene Details

• Entrez Gene ID: 650669
• Gene Name: GAS6 antisense RNA 1
• Gene Aliases: -
• Location: Chr.13:113815610-113842841 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GAS6-AS1	NR_044995.2
	DA460725.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv563390	Chr.13:113809317 - 113845944 on Build GRCh38	Loss	GAS6-AS1 TMEM255B GAS6
nsv1043348	Chr.13:113756321 - 113867896 on Build GRCh38	Gain	LOC105377805 GAS6-AS2 GAS6-AS1 TMEM255B GAS6
nsv951933	Chr.13:113808028 - 113844427 on Build GRCh38	Deletion	GAS6-AS1 TMEM255B GAS6
dgv3450n54	Chr.13:113754200 - 113886735 on Build GRCh38	Gain	LOC105377805 LINC00454 GAS6-AS2 GAS6-AS1 TMEM255B GAS6
nsv832727	Chr.13:113753115 - 113918257 on Build GRCh38	Loss	LOC105377805 LINC00454 GAS6-AS2 GAS6-AS1 TMEM255B GAS6 LINC00452
nsv563387	Chr.13:113832338 - 113876058 on Build GRCh38	Loss	GAS6-AS2 GAS6-AS1 GAS6
esv3582860	Chr.13:113756381 - 113867871 on Build GRCh38	Gain	LOC105377805 GAS6-AS2 GAS6-AS1 TMEM255B GAS6
nsv826836	Chr.13:113753163 - 113875076 on Build GRCh38	Loss	LOC105377805 GAS6-AS2 GAS6-AS1 TMEM255B GAS6
esv3633615	Chr.13:113724844 - 113843481 on Build GRCh38	Gain	LOC105377805 LINC00552 GRK1 GAS6-AS1 TMEM255B GAS6

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

extracellular matrix protein

Gene Ontology Categories:

Process(es)

neuron migration
positive regulation of protein phosphorylation
positive regulation of cytokine-mediated signaling pathway
platelet degranulation
positive regulation of glomerular filtration
signal peptide processing
protein phosphorylation
ER to Golgi vesicle-mediated transport
phagocytosis
apoptotic process
cell cycle arrest
cell adhesion
signal transduction
enzyme linked receptor protein signaling pathway
cell proliferation
cellular response to starvation
positive regulation of gene expression
negative regulation of tumor necrosis factor-mediated signaling pathway
macrophage cytokine production
cell migration
peptidyl-serine phosphorylation
fusion of virus membrane with host plasma membrane
viral genome replication
platelet activation
organ regeneration
cell-substrate adhesion
positive regulation of TOR signaling
activation of protein kinase B activity
negative regulation of interferon-gamma production
negative regulation of interleukin-6 production
negative regulation of tumor necrosis factor production
positive regulation of natural killer cell differentiation
positive regulation of peptidyl-serine phosphorylation
negative regulation of protein import into nucleus, translocation
cellular response to interferon-alpha
cellular response to drug
B cell chemotaxis
regulation of growth
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
apoptotic cell clearance
negative regulation of sequence-specific DNA binding transcription factor activity
protein kinase B signaling
positive regulation of protein kinase activity
negative regulation of transcription, DNA-templated
viral entry into host cell
receptor-mediated virion attachment to host cell
positive regulation of protein export from nucleus
positive regulation of fibroblast proliferation
negative regulation of interleukin-1 secretion
positive regulation of phagocytosis
leukocyte migration
positive regulation of protein kinase B signaling
positive regulation of protein tyrosine kinase activity
negative regulation of biomineral tissue development
positive regulation of ERK1 and ERK2 cascade
platelet aggregation
calcium ion transmembrane transport
cellular response to vitamin K
cellular response to glucose stimulus
cellular response to growth factor stimulus
protein targeting to plasma membrane
extracellular matrix assembly
dendritic cell differentiation
hematopoietic stem cell migration to bone marrow
negative regulation of oligodendrocyte apoptotic process
negative regulation of interleukin-6 secretion
negative regulation of fibroblast apoptotic process
negative regulation of endothelial cell apoptotic process
positive regulation of dendritic cell chemotaxis
negative regulation of renal albumin absorption
negative regulation of dendritic cell apoptotic process

Function(s)

phosphatidylserine binding
receptor binding
voltage-gated calcium channel activity
calcium ion binding
protein binding
protein tyrosine kinase activator activity
receptor tyrosine kinase binding
cysteine-type endopeptidase inhibitor activity involved in apoptotic process
receptor agonist activity
binding, bridging