Hs03919263_cn

• Gene Symbol: CBFA2T3
• Assay Reference Genome Location: Chr.16:88881668 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 863
• Gene Name: CBFA2/RUNX1 translocation partner 3
• Gene Aliases: ETO2, MTG16, MTGR2, RUNX1T3, ZMYND4
• Location: Chr.16:88874855-88977198 on Build GRCh38
• Assay Gene Location: Within Intron 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CBFA2T3	NM_005187.5			NP_005178.4
	NM_175931.2			NP_787127.1
	XM_005256323.4			XP_005256380.1
	XM_011523419.2			XP_011521721.1
	XM_017023811.1			XP_016879300.1
	AB010419.1			BAA29061.1
	AB010420.1			BAA29062.1
	AF052220.1			AAC64698.1
	AK308355.1
	AK314766.1
	BC047019.1
	BC062624.1			AAH62624.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv37n68	Chr.16:88767460 - 88944903 on Build GRCh38	Loss	LOC101927793 PABPN1L LOC107987238 TRAPPC2L PIEZO1 LOC105371409 GALNS APRT CDT1 LOC100129697 CBFA2T3
nsv1063024	Chr.16:88707330 - 89238482 on Build GRCh38	Gain	LOC101927793 PABPN1L SLC22A31 LOC107987238 MIR4722 LOC100289580 LOC105371409 GALNS CTU2 APRT CDH15 LOC400558 TRAPPC2L PIEZO1 LINC00304 ACSF3 ZNF778 LOC339059 CDT1 LOC100129697 CBFA2T3
nsv1928	Chr.16:88865211 - 88897277 on Build GRCh38	Insertion	LOC101927793 PABPN1L CBFA2T3
nsv471115	Chr.16:88801844 - 89197442 on Build GRCh38	Loss	LOC101927793 PABPN1L SLC22A31 LOC107987238 LOC105371409 GALNS APRT CDH15 LOC400558 TRAPPC2L LINC00304 ACSF3 CDT1 LOC100129697 CBFA2T3
nsv573674	Chr.16:88738775 - 89325907 on Build GRCh38	Gain	LOC101927793 PABPN1L SLC22A31 LOC107987238 LOC105371414 LOC100289580 LOC105371409 GALNS APRT CDH15 LOC400558 TRAPPC2L PIEZO1 LINC00304 ACSF3 ANKRD11 ZNF778 LOC339059 CDT1 LOC100287036 LOC100129697 CBFA2T3
esv3639555	Chr.16:88745961 - 88899576 on Build GRCh38	Gain	LOC101927793 PABPN1L LOC107987238 TRAPPC2L PIEZO1 GALNS APRT CDT1 CBFA2T3
nsv952071	Chr.16:88790893 - 89019992 on Build GRCh38	Deletion	LOC101927793 PABPN1L LOC107987238 TRAPPC2L LOC105371409 GALNS APRT CDT1 LOC100129697 CBFA2T3
nsv521217	Chr.16:88805821 - 89174375 on Build GRCh38	Loss	LOC101927793 PABPN1L LOC107987238 LOC105371409 GALNS APRT CDH15 LOC400558 TRAPPC2L LINC00304 ACSF3 CDT1 LOC100129697 CBFA2T3
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	LOC105371414 SNORD68 LOC101927817 LOC105371409 RPL13 LOC400558 CYBA TCF25 LOC105371419 PABPN1L SLC22A31 VPS9D1-AS1 MIR4722 CHMP1A VPS9D1 AFG3L1P TUBB8P7 DBNDD1 LINC00304 DPEP1 ANKRD11 ZNF778 FAM157C LOC339059 CBFA2T3 GAS8-AS1 LOC101927793 PRDM7 SPIRE2 LOC107987238 IL17C LOC100289580 TUBB3 FANCA GALNS CDK10 CTU2 LOC107984817 SPATA33 APRT CDH15 MVD CENPBD1 TRAPPC2L RNF166 PIEZO1 SPG7 SNAI3 CDT1 ZNF276 LOC100287036 LOC100129697 MC1R URAHP DEF8 GAS8 SPATA2L ACSF3 CPNE7 SNAI3-AS1
esv3639561	Chr.16:88837996 - 88882065 on Build GRCh38	Gain	PABPN1L TRAPPC2L GALNS CBFA2T3
nsv1061256	Chr.16:88711587 - 89013365 on Build GRCh38	Gain	LOC101927793 PABPN1L LOC107987238 MIR4722 LOC100289580 LOC105371409 GALNS CTU2 APRT TRAPPC2L PIEZO1 LOC339059 CDT1 LOC100129697 CBFA2T3

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transcription cofactor

Gene Ontology Categories:

Process(es)

response to hypoxia
transcription, DNA-templated
cell proliferation
negative regulation of cell proliferation
granulocyte differentiation
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
negative regulation of glycolytic process
negative regulation of transcription, DNA-templated
regulation of aerobic respiration

Function(s)

transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
protein binding
metal ion binding