Hs03930639_cn

• Gene Symbol: NDUFB10
• Assay Reference Genome Location: Chr.16:1960643 on build GRCh38
• Cytoband: 16p13.3

Target Gene Details

• Entrez Gene ID: 4716
• Gene Name: NADH:ubiquinone oxidoreductase subunit B10
• Gene Aliases: PDSW
• Location: Chr.16:1959516-1961975 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NDUFB10	NM_004548.2			NP_004539.1
	AF044954.1			AAD05419.1
	AF067169.1			AAD32453.1
	AF088991.1			AAD08677.1
	AK291876.1
	AK311744.1
	BC005829.2			AAH05829.1
	BC007509.2			AAH07509.1
	BP319067.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2422427	Chr.16:10001 - 2723164 on Build GRCh38	Duplication	HN1L CCDC154 MAPK8IP3 HAGHL MIR6767 CAPN15 UBE2I EME2 RPS2 MPG PRSS27 FBXL16 RPUSD1 RAB26 CEMP1 MIR1225 FLJ42627 MIR3180-5 NARFL PRR25 LOC107987233 KCTD5 MEIOB SNORD60 LOC106660606 HBZ TBL3 LOC729652 LINC00254 SYNGR3 SPSB3 WFIKKN1 HBQ1 HBA2 HBM LOC105371047 LOC100287175 DNASE1L2 PDPK1 SNRNP25 NTN3 SLC9A3R2 C1QTNF8 PTX4 LOC652276 LOC107984876 SNORA64 TMEM8A MIR6859-4 E4F1 POLR3K BRICD5 ZNF598 RAB40C RHBDF1 RNF151 HS3ST6 WDR24 MIR5587 RAB11FIP3 CCDC78 RNPS1 RPL23AP5 LINC00235 DECR2 ABCA3 NTHL1 SNHG19 SSTR5 UNKL ERVK13-1 JMJD8 SNHG9 MRPS34 LOC105371045 CLCN7 MIR3178 HAGH MIR4516 BAIAP3 CHTF18 MLST8 MIR662 TPSD1 ATP6V0C SNORA10 MIR6768 PKD1 NME4 NPW METRN MIR4717 TELO2 FAM173A LOC105371038 FAM234A STUB1 TRAF7 MSRB1 CRAMP1 WASIR2 LOC105371046 NOXO1 MRPL28 LMF1 TSC2 NPRL3 TSR3 GNG13 MCRIP2 PRSS29P DDX11L10 RGS11 C16orf91 LOC101929280 CACNA1H MIR3677 FAHD1 IGFALS GFER AMDHD2 ARHGDIG MIR940 LOC105371049 PDIA2 SSTR5-AS1 WDR90 LMF1-AS1 ECI1 RPL3L MSLN NUBP2 SOX8 AXIN1 MIR6511B1 METTL26 PGP TBC1D24 TMEM204 NHLRC4 PIGQ C16orf59 LOC100134368 NDUFB10 TPSAB1 CCNF MIR3177 HBA1 TPSG1 RHOT2 NME3 SNORA78 GNPTG ABCA17P TPSB2 LOC105371184 MIR3176 RHBDL1 PRR35 LUC7L IFT140 CASKIN1
nsv952901	Chr.16:1888800 - 2135899 on Build GRCh38	Deletion	PKD1 SNHG9 RPL3L ZNF598 NPW RPS2 TBL3 RNF151 MIR6511B1 SNORA78 HS3ST6 SYNGR3 GFER MIR4516 LOC105371049 MSRB1 MIR1225 NTHL1 NOXO1 NDUFB10 SLC9A3R2 SNORA10 TSC2 SNORA64
dgv4858n54	Chr.16:1955562 - 2038584 on Build GRCh38	Loss	SNHG9 ZNF598 NPW RPS2 TBL3 RNF151 SNORA78 SYNGR3 GFER NOXO1 NDUFB10 SLC9A3R2 SNORA10 SNORA64
nsv571179	Chr.16:1947613 - 1995730 on Build GRCh38	Loss	SNHG9 RPL3L RPS2 TBL3 NOXO1 RNF151 NDUFB10 SNORA78 SNORA10 SYNGR3 GFER SNORA64
nsv519366	Chr.16:1851210 - 1961125 on Build GRCh38	Loss	RPL3L MEIOB MSRB1 NDUFB10 HS3ST6 LINC00254
nsv833120	Chr.16:1893102 - 1980660 on Build GRCh38	Loss	SNHG9 RPL3L MSRB1 RPS2 TBL3 NOXO1 RNF151 NDUFB10 SNORA78 HS3ST6 SNORA10 SNORA64
nsv571178	Chr.16:1919082 - 1961125 on Build GRCh38	Loss	RPL3L MSRB1 NDUFB10 HS3ST6

More Information

Additional Information:

For this assay, SNP(s) [rs74391990] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

oxidoreductase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

mitochondrial electron transport, NADH to ubiquinone
mitochondrial respiratory chain complex I assembly

Function(s)

protein binding
NADH dehydrogenase (ubiquinone) activity