Hs03930639_cn

• Gene Symbol: NDUFB10
• Assay Reference Genome Location: Chr.16:1960643 on build GRCh38
• Cytoband: 16p13.3

Target Gene Details

• Entrez Gene ID: 4716
• Gene Name: NADH:ubiquinone oxidoreductase subunit B10
• Gene Aliases: PDSW
• Location: Chr.16:1959516-1961975 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NDUFB10	NM_004548.2			NP_004539.1
	AF044954.1			AAD05419.1
	AF067169.1			AAD32453.1
	AF088991.1			AAD08677.1
	AK291876.1
	AK311744.1
	BC005829.2			AAH05829.1
	BC007509.2			AAH07509.1
	BP319067.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2422427	Chr.16:10001 - 2723164 on Build GRCh38	Duplication	ATP6V0C ARHGDIG MIR3180-5 METRN WDR90 RNF151 CEMP1 GNG13 LOC105371046 PIGQ DNASE1L2 MIR1225 NHLRC4 CCDC154 MIR5587 TELO2 NTHL1 RAB11FIP3 MIR3177 WFIKKN1 WDR24 IFT140 BAIAP3 LMF1-AS1 PRR35 MPG PDIA2 NARFL TMEM204 TPSAB1 MSLN IGFALS METTL26 CASKIN1 SNRNP25 SNORD60 CACNA1H HAGH SNORA78 RHOT2 SSTR5 LOC106660606 GFER SPSB3 DDX11L10 KCTD5 NME3 LOC100134368 PRSS29P LOC107987233 SNHG19 RAB26 HBA2 CHTF18 RHBDF1 NUBP2 NTN3 SNORA10 PRR25 BRICD5 RGS11 MIR940 UBE2I TSC2 MIR6767 NME4 CAPN15 RPL3L LOC105371038 TSR3 HN1L RAB40C C16orf91 LOC101929280 HAGHL TPSG1 NDUFB10 ABCA17P SLC9A3R2 CLCN7 MSRB1 LOC652276 CRAMP1 SNORA64 HS3ST6 FBXL16 C1QTNF8 TMEM8A JMJD8 UNKL MRPL28 TBC1D24 NPW C16orf59 SSTR5-AS1 MEIOB LOC105371049 LOC100287175 PGP RPUSD1 HBA1 MIR4516 DECR2 PDPK1 RHBDL1 STUB1 MIR3176 SNHG9 MIR4717 FLJ42627 LOC729652 TRAF7 E4F1 PTX4 POLR3K LOC105371047 AMDHD2 AXIN1 RNPS1 FAM234A LOC107984876 MIR6859-4 MIR3677 LUC7L LOC105371184 SOX8 MCRIP2 PKD1 PRSS27 HBM CCDC78 NPRL3 MAPK8IP3 HBQ1 EME2 MLST8 RPL23AP5 ECI1 ERVK13-1 LMF1 ABCA3 MIR6511B1 FAHD1 CCNF LINC00254 ZNF598 MIR6768 SYNGR3 WASIR2 MRPS34 MIR3178 TPSD1 LINC00235 TBL3 MIR662 HBZ FAM173A LOC105371045 NOXO1 RPS2 TPSB2 GNPTG
dgv4858n54	Chr.16:1955562 - 2038584 on Build GRCh38	Loss	SLC9A3R2 ZNF598 SYNGR3 GFER RNF151 SNORA64 TBL3 SNHG9 NOXO1 SNORA78 RPS2 NPW NDUFB10 SNORA10
nsv952901	Chr.16:1888800 - 2135899 on Build GRCh38	Deletion	SLC9A3R2 MSRB1 LOC105371049 ZNF598 TSC2 SYNGR3 GFER RPL3L MIR4516 RNF151 SNORA64 PKD1 HS3ST6 TBL3 SNHG9 MIR1225 NOXO1 NTHL1 SNORA78 RPS2 NPW NDUFB10 MIR6511B1 SNORA10
nsv471070	Chr.16:1947613 - 2024218 on Build GRCh38	Gain	ZNF598 SYNGR3 GFER RPL3L RNF151 SNORA64 TBL3 SNHG9 NOXO1 SNORA78 RPS2 NPW NDUFB10 SNORA10
nsv833120	Chr.16:1893102 - 1980660 on Build GRCh38	Loss	HS3ST6 TBL3 SNHG9 MSRB1 NOXO1 SNORA78 RPS2 RPL3L RNF151 SNORA64 NDUFB10 SNORA10
nsv519366	Chr.16:1851210 - 1961125 on Build GRCh38	Loss	LINC00254 HS3ST6 MEIOB MSRB1 RPL3L NDUFB10
nsv571178	Chr.16:1919082 - 1961125 on Build GRCh38	Loss	HS3ST6 MSRB1 RPL3L NDUFB10

More Information

Additional Information:

For this assay, SNP(s) [rs74391990] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

oxidoreductase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

mitochondrial electron transport, NADH to ubiquinone
mitochondrial respiratory chain complex I assembly

Function(s)

protein binding
NADH dehydrogenase (ubiquinone) activity