Hs03931415_cn

• Gene Symbol: CBFA2T3
• Assay Reference Genome Location: Chr.16:88881987 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 863
• Gene Name: CBFA2/RUNX1 translocation partner 3
• Gene Aliases: ETO2, MTG16, MTGR2, RUNX1T3, ZMYND4
• Location: Chr.16:88874855-88977198 on Build GRCh38
• Assay Gene Location: Within Intron 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CBFA2T3	NM_005187.5			NP_005178.4
	NM_175931.2			NP_787127.1
	XM_005256323.4			XP_005256380.1
	XM_011523419.2			XP_011521721.1
	XM_017023811.1			XP_016879300.1
	AB010419.1			BAA29061.1
	AB010420.1			BAA29062.1
	AF052220.1			AAC64698.1
	AK308355.1
	AK314766.1
	BC047019.1
	BC062624.1			AAH62624.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv37n68	Chr.16:88767460 - 88944903 on Build GRCh38	Loss	LOC101927793 CDT1 LOC107987238 LOC100129697 PIEZO1 GALNS LOC105371409 PABPN1L TRAPPC2L CBFA2T3 APRT
nsv1063024	Chr.16:88707330 - 89238482 on Build GRCh38	Gain	CDT1 LOC400558 ACSF3 LOC107987238 MIR4722 PIEZO1 CTU2 LINC00304 LOC105371409 TRAPPC2L LOC101927793 LOC339059 LOC100289580 LOC100129697 SLC22A31 GALNS ZNF778 CDH15 PABPN1L CBFA2T3 APRT
nsv1928	Chr.16:88865211 - 88897277 on Build GRCh38	Insertion	LOC101927793 PABPN1L CBFA2T3
nsv471115	Chr.16:88801844 - 89197442 on Build GRCh38	Loss	CDT1 LOC400558 ACSF3 LOC107987238 LINC00304 LOC105371409 TRAPPC2L LOC101927793 LOC100129697 SLC22A31 GALNS CDH15 PABPN1L CBFA2T3 APRT
nsv573674	Chr.16:88738775 - 89325907 on Build GRCh38	Gain	LOC105371414 LOC100287036 CDT1 LOC400558 ANKRD11 ACSF3 LOC107987238 PIEZO1 LINC00304 LOC105371409 TRAPPC2L LOC101927793 LOC339059 LOC100289580 LOC100129697 SLC22A31 GALNS ZNF778 CDH15 PABPN1L CBFA2T3 APRT
esv3639555	Chr.16:88745961 - 88899576 on Build GRCh38	Gain	LOC101927793 CDT1 LOC107987238 PIEZO1 GALNS PABPN1L TRAPPC2L CBFA2T3 APRT
nsv521217	Chr.16:88805821 - 89174375 on Build GRCh38	Loss	CDT1 LOC400558 ACSF3 LOC107987238 LINC00304 LOC105371409 TRAPPC2L LOC101927793 LOC100129697 GALNS CDH15 PABPN1L CBFA2T3 APRT
nsv952071	Chr.16:88790893 - 89019992 on Build GRCh38	Deletion	LOC101927793 CDT1 LOC107987238 LOC100129697 GALNS LOC105371409 PABPN1L TRAPPC2L CBFA2T3 APRT
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	CTU2 LINC00304 SPIRE2 SLC22A31 LOC107984817 CENPBD1 APRT GAS8 CDT1 ANKRD11 ACSF3 LOC107987238 ZNF276 TUBB3 CDK10 AFG3L1P MC1R LOC105371409 TCF25 LOC100289580 LOC100129697 IL17C SPG7 ZNF778 URAHP GAS8-AS1 LOC105371414 VPS9D1 DPEP1 LOC400558 CPNE7 MIR4722 RPL13 SNORD68 TRAPPC2L LOC101927793 PRDM7 CHMP1A LOC339059 SNAI3 TUBB8P7 DEF8 SPATA2L RNF166 CBFA2T3 LOC100287036 MVD DBNDD1 PIEZO1 VPS9D1-AS1 LOC105371419 LOC101927817 SPATA33 FAM157C SNAI3-AS1 CYBA GALNS FANCA CDH15 PABPN1L
esv3639561	Chr.16:88837996 - 88882065 on Build GRCh38	Gain	GALNS PABPN1L TRAPPC2L CBFA2T3
nsv1061256	Chr.16:88711587 - 89013365 on Build GRCh38	Gain	CDT1 LOC107987238 MIR4722 PIEZO1 CTU2 LOC105371409 TRAPPC2L LOC101927793 LOC339059 LOC100289580 LOC100129697 GALNS PABPN1L CBFA2T3 APRT

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transcription cofactor

Gene Ontology Categories:

Process(es)

response to hypoxia
transcription, DNA-templated
cell proliferation
negative regulation of cell proliferation
granulocyte differentiation
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
negative regulation of glycolytic process
negative regulation of transcription, DNA-templated
regulation of aerobic respiration

Function(s)

transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
protein binding
metal ion binding