Hs03979464_cn

• Gene Symbol: HDAC5
• Assay Reference Genome Location: Chr.17:44119666 on build GRCh38
• Cytoband: 17q21.31

Target Gene Details

• Entrez Gene ID: 10014
• Gene Name: histone deacetylase 5
• Gene Aliases: HD5, NY-CO-9
• Location: Chr.17:44076753-44123646 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
HDAC5	NM_001015053.1			NP_001015053.1
	NM_005474.4			NP_005465.2
	XM_005256905.1			XP_005256962.1
	XM_005256906.4			XP_005256963.1
	XM_011524149.1			XP_011522451.1
	XM_011524150.1			XP_011522452.1
	XM_017023988.1			XP_016879477.1
	XM_017023989.1			XP_016879478.1
	XM_017023990.1			XP_016879479.1
	XM_017023991.1			XP_016879480.1
	XM_017023992.1			XP_016879481.1
	XM_017023993.1			XP_016879482.1
	XM_017023995.1			XP_016879484.1
	XM_017023996.1			XP_016879485.1
	AB011172.2			BAA25526.2
	AK294760.1
	BC051824.1			AAH51824.1
	BM564861.1
	CN290533.1

Target Gene Details

• Entrez Gene ID: 105371789
• Gene Name: uncharacterized LOC105371789
• Gene Aliases: -
• Location: Chr.17:44115912-44120595 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LOC105371789	NR_136415.1
	DB338921.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833454	Chr.17:43940848 - 44158311 on Build GRCh38	Loss	LOC105371789 TMEM101 C17orf53 G6PC3 HDAC5 PPY NAGS PYY LSM12
nsv833455	Chr.17:44108553 - 44297300 on Build GRCh38	Loss	LOC105371789 ATXN7L3 ASB16 C17orf53 TMUB2 MIR6782 HDAC5 LOC101926967 ASB16-AS1 UBTF SLC4A1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

histone modifying enzyme

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
chromatin organization
chromatin remodeling
chromatin silencing
transcription, DNA-templated
protein deacetylation
inflammatory response
regulation of myotube differentiation
negative regulation of myotube differentiation
response to activity
chromatin modification
histone deacetylation
neuron differentiation
B cell differentiation
cellular response to insulin stimulus
regulation of gene expression, epigenetic
B cell activation
response to cocaine
response to drug
regulation of protein binding
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of sequence-specific DNA binding transcription factor activity
histone H3 deacetylation
cellular response to lipopolysaccharide
negative regulation of cell migration involved in sprouting angiogenesis
regulation of histone H3-K9 acetylation

Function(s)

RNA polymerase III transcription factor binding
core promoter binding
chromatin binding
histone deacetylase activity
protein kinase C binding
protein binding
transcription factor binding
NAD-dependent histone deacetylase activity (H3-K14 specific)
protein deacetylase activity
histone deacetylase binding
transcription regulatory region DNA binding
metal ion binding
repressing transcription factor binding