Hs03993306_cn

• Gene Symbol: SERPINB10
• Assay Reference Genome Location: Chr.18:63923188 on build GRCh38
• Cytoband: 18q22.1

Target Gene Details

• Entrez Gene ID: 5273
• Gene Name: serpin family B member 10
• Gene Aliases: PI-10, PI10
• Location: Chr.18:63907969-63936111 on Build GRCh38
• Assay Gene Location: Within Intron 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SERPINB10	NM_005024.2			NP_005015.1
	XM_011526027.1			XP_011524329.1
	XM_011526028.1			XP_011524330.1
	XM_017025793.1			XP_016881282.1
	XM_017025794.1			XP_016881283.1
	AK314936.1
	BC096217.3			AAH96217.1
	BC096218.3			AAH96218.1
	BC096219.3			AAH96219.1
	BC096220.3			AAH96220.1
	U35459.1			AAC50282.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1066552	Chr.18:63147299 - 64608176 on Build GRCh38	Gain	SERPINB8 SERPINB7 SERPINB12 LOC284294 SERPINB5 SERPINB3 LINC01538 SERPINB2 SERPINB13 KDSR HMSD SERPINB4 SERPINB10 SERPINB11 BCL2 VPS4B LINC00305
nsv833673	Chr.18:63897072 - 64097021 on Build GRCh38	Gain	SERPINB8 SERPINB2 HMSD SERPINB10 LINC00305
esv3642785	Chr.18:63831255 - 63986077 on Build GRCh38	Gain	SERPINB8 SERPINB2 HMSD SERPINB10
esv21739	Chr.18:63715122 - 64278129 on Build GRCh38	Gain	LINC01538 SERPINB8 SERPINB2 SERPINB7 HMSD SERPINB10 SERPINB11 LOC284294 LINC00305
nsv1067311	Chr.18:63818011 - 66637685 on Build GRCh38	Loss	LINC01538 SERPINB8 SERPINB2 HMSD CDH7 SERPINB10 CDH19 LOC284294 LINC00305
esv2758730	Chr.18:63881807 - 63923851 on Build GRCh38	Loss	SERPINB2 SERPINB10
nsv525889	Chr.18:63845132 - 63948110 on Build GRCh38	Loss	SERPINB2 SERPINB10
esv3642788	Chr.18:63922332 - 63954216 on Build GRCh38	Gain	HMSD SERPINB10

More Information

Additional Information:

For this assay, SNP(s) [rs73961814] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protease inhibitor

Gene Ontology Categories:

Process(es)

positive regulation of defense response to virus by host
negative regulation of endopeptidase activity
mitophagy in response to mitochondrial depolarization
xenophagy

Function(s)

serine-type endopeptidase inhibitor activity