Hs04003622_cn

• Gene Symbol: SERPINB10
• Assay Reference Genome Location: Chr.18:63910000 on build GRCh38
• Cytoband: 18q22.1

Target Gene Details

• Entrez Gene ID: 5273
• Gene Name: serpin family B member 10
• Gene Aliases: PI-10, PI10
• Location: Chr.18:63907969-63936111 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SERPINB10	NM_005024.2			NP_005015.1
	XM_011526027.1			XP_011524329.1
	XM_017025793.1			XP_016881282.1
	XM_017025794.1			XP_016881283.1
	AK314936.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1066552	Chr.18:63147299 - 64608176 on Build GRCh38	Gain	SERPINB5 LINC00305 KDSR SERPINB3 BCL2 HMSD LINC01538 SERPINB11 SERPINB8 SERPINB7 LOC284294 SERPINB12 SERPINB10 SERPINB13 SERPINB4 SERPINB2 VPS4B
nsv833673	Chr.18:63897072 - 64097021 on Build GRCh38	Gain	SERPINB8 LINC00305 SERPINB10 SERPINB2 HMSD
esv21739	Chr.18:63715122 - 64278129 on Build GRCh38	Gain	SERPINB11 SERPINB8 LINC00305 SERPINB7 LOC284294 SERPINB10 SERPINB2 HMSD LINC01538
esv3642785	Chr.18:63831255 - 63986077 on Build GRCh38	Gain	SERPINB8 SERPINB10 SERPINB2 HMSD
nsv1067311	Chr.18:63818011 - 66637685 on Build GRCh38	Loss	SERPINB8 LINC00305 CDH7 LOC284294 CDH19 SERPINB10 SERPINB2 HMSD LINC01538
nsv525889	Chr.18:63845132 - 63948110 on Build GRCh38	Loss	SERPINB10 SERPINB2
esv2758730	Chr.18:63881807 - 63923851 on Build GRCh38	Loss	SERPINB10 SERPINB2

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protease inhibitor

Gene Ontology Categories:

Process(es)

positive regulation of defense response to virus by host
negative regulation of endopeptidase activity
mitophagy in response to mitochondrial depolarization
xenophagy

Function(s)

serine-type endopeptidase inhibitor activity