Hs04013567_cn

• Gene Symbol: FSTL3
• Assay Reference Genome Location: Chr.19:679598 on build GRCh38
• Cytoband: 19p13.3

Target Gene Details

• Entrez Gene ID: 10272
• Gene Name: follistatin like 3
• Gene Aliases: FLRG, FSRP
• Location: Chr.19:676389-683392 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
FSTL3	NM_005860.2			NP_005851.1
	AK291958.1
	AK313341.1
	AY358917.1			AAQ89276.1
	BC005839.2			AAH05839.1
	BX439786.2
	U76702.1			AAC64321.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv578163	Chr.19:629303 - 682010 on Build GRCh38	Loss	FSTL3 POLRMT FGF22 RNF126
dgv134n111	Chr.19:607984 - 967584 on Build GRCh38	Deletion	POLRMT HCN2 PRSS57 AZU1 MIR3187 PLPPR3 PRTN3 MIR4745 R3HDM4 FGF22 PALM MISP RNF126 ELANE RNU6-9 FSTL3 LOC101928450 KISS1R PTBP1 CFD MED16 ARID3A
nsv428360	Chr.19:232069 - 702131 on Build GRCh38	Gain	CDC34 POLRMT HCN2 PRSS57 ODF3L2 LOC101929060 FGF22 SHC2 RNF126 BSG MADCAM1 TPGS1 PLPP2 FSTL3 MIER2 GZMM C2CD4C THEG
nsv577978	Chr.19:294526 - 782854 on Build GRCh38	Gain	CDC34 POLRMT HCN2 PRSS57 ODF3L2 LOC101929060 FGF22 SHC2 PALM MISP RNF126 BSG MADCAM1 TPGS1 FSTL3 MIER2 LOC101928450 GZMM C2CD4C THEG
nsv953938	Chr.19:355801 - 1104501 on Build GRCh38	Deletion	CDC34 POLRMT HCN2 LOC105372235 PRSS57 ODF3L2 PLPPR3 PRTN3 MIR4745 PALM MISP RNF126 ELANE MADCAM1 TPGS1 FSTL3 KISS1R PTBP1 ARID3A CNN2 C2CD4C THEG ABCA7 AZU1 MIR3187 POLR2E R3HDM4 FGF22 SHC2 GPX4 WDR18 BSG GRIN3B RNU6-2 RNU6-9 LOC101928450 CFD MED16 GZMM ARHGAP45 TMEM259
nsv470101	Chr.19:401714 - 1008505 on Build GRCh38	Loss	CDC34 POLRMT HCN2 LOC105372235 PRSS57 ODF3L2 PLPPR3 PRTN3 MIR4745 PALM MISP RNF126 ELANE MADCAM1 TPGS1 FSTL3 KISS1R PTBP1 ARID3A C2CD4C AZU1 MIR3187 R3HDM4 FGF22 SHC2 WDR18 BSG GRIN3B RNU6-9 LOC101928450 CFD MED16 GZMM

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

extracellular matrix glycoprotein

Gene Ontology Categories:

Process(es)

ossification
kidney development
hematopoietic progenitor cell differentiation
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
spermatogenesis
male gonad development
positive regulation of cell-cell adhesion
lung development
adrenal gland development
negative regulation of BMP signaling pathway
negative regulation of activin receptor signaling pathway
negative regulation of osteoclast differentiation
positive regulation of transcription from RNA polymerase II promoter
cellular response to metal ion
negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

Function(s)

fibronectin binding
protein binding
activin binding