Hs04015673_cn

• Gene Symbol: FSTL3
• Assay Reference Genome Location: Chr.19:679922 on build GRCh38
• Cytoband: 19p13.3

Target Gene Details

• Entrez Gene ID: 10272
• Gene Name: follistatin like 3
• Gene Aliases: FLRG, FSRP
• Location: Chr.19:676389-683392 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
FSTL3	NM_005860.2			NP_005851.1
	AK291958.1
	AK313341.1
	AY358917.1			AAQ89276.1
	BC005839.2			AAH05839.1
	BX439786.2
	U76702.1			AAC64321.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv578163	Chr.19:629303 - 682010 on Build GRCh38	Loss	FSTL3 RNF126 FGF22 POLRMT
dgv134n111	Chr.19:607984 - 967584 on Build GRCh38	Deletion	KISS1R PTBP1 FSTL3 MED16 R3HDM4 ELANE PRSS57 MIR4745 ARID3A FGF22 PALM MISP CFD RNU6-9 MIR3187 PLPPR3 LOC101928450 HCN2 RNF126 AZU1 PRTN3 POLRMT
nsv428360	Chr.19:232069 - 702131 on Build GRCh38	Gain	FSTL3 CDC34 SHC2 ODF3L2 MADCAM1 PRSS57 BSG FGF22 LOC101929060 TPGS1 THEG C2CD4C MIER2 PLPP2 GZMM HCN2 RNF126 POLRMT
nsv577978	Chr.19:294526 - 782854 on Build GRCh38	Gain	FSTL3 CDC34 SHC2 ODF3L2 MADCAM1 PRSS57 BSG FGF22 LOC101929060 TPGS1 THEG PALM C2CD4C MISP MIER2 GZMM LOC101928450 HCN2 RNF126 POLRMT
nsv953938	Chr.19:355801 - 1104501 on Build GRCh38	Deletion	KISS1R ODF3L2 R3HDM4 ABCA7 LOC105372235 ELANE PRSS57 MIR4745 ARID3A THEG PALM POLR2E MIR3187 GZMM PTBP1 GRIN3B TMEM259 FSTL3 MED16 CDC34 WDR18 SHC2 ARHGAP45 MADCAM1 BSG FGF22 CNN2 RNU6-2 TPGS1 GPX4 C2CD4C MISP CFD RNU6-9 PLPPR3 LOC101928450 HCN2 RNF126 AZU1 PRTN3 POLRMT
nsv470101	Chr.19:401714 - 1008505 on Build GRCh38	Loss	KISS1R ODF3L2 R3HDM4 LOC105372235 ELANE PRSS57 MIR4745 ARID3A PALM MIR3187 GZMM PTBP1 GRIN3B FSTL3 MED16 CDC34 WDR18 SHC2 MADCAM1 BSG FGF22 TPGS1 C2CD4C MISP CFD RNU6-9 PLPPR3 LOC101928450 HCN2 RNF126 AZU1 PRTN3 POLRMT

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

extracellular matrix glycoprotein

Gene Ontology Categories:

Process(es)

ossification
kidney development
hematopoietic progenitor cell differentiation
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
spermatogenesis
male gonad development
positive regulation of cell-cell adhesion
lung development
adrenal gland development
negative regulation of BMP signaling pathway
negative regulation of activin receptor signaling pathway
negative regulation of osteoclast differentiation
positive regulation of transcription from RNA polymerase II promoter
cellular response to metal ion
negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

Function(s)

fibronectin binding
protein binding
activin binding