Hs04024436_cn

• Gene Symbol: FSTL3
• Assay Reference Genome Location: Chr.19:677410 on build GRCh38
• Cytoband: 19p13.3

Target Gene Details

• Entrez Gene ID: 10272
• Gene Name: follistatin like 3
• Gene Aliases: FLRG, FSRP
• Location: Chr.19:676389-683392 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
FSTL3	NM_005860.2			NP_005851.1
	AK291958.1
	AK313341.1
	AY358917.1			AAQ89276.1
	BC005839.2			AAH05839.1
	BX439786.2
	U76702.1			AAC64321.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv578163	Chr.19:629303 - 682010 on Build GRCh38	Loss	FSTL3 RNF126 POLRMT FGF22
dgv134n111	Chr.19:607984 - 967584 on Build GRCh38	Deletion	PRTN3 ELANE RNF126 CFD ARID3A POLRMT AZU1 PTBP1 PRSS57 KISS1R MIR3187 PALM FSTL3 RNU6-9 LOC101928450 PLPPR3 MIR4745 R3HDM4 HCN2 MED16 FGF22 MISP
nsv428360	Chr.19:232069 - 702131 on Build GRCh38	Gain	BSG LOC101929060 RNF126 POLRMT PRSS57 GZMM THEG SHC2 MADCAM1 FSTL3 TPGS1 ODF3L2 CDC34 HCN2 C2CD4C MIER2 FGF22 PLPP2
nsv577978	Chr.19:294526 - 782854 on Build GRCh38	Gain	BSG LOC101929060 RNF126 POLRMT PRSS57 PALM GZMM THEG SHC2 MADCAM1 FSTL3 TPGS1 LOC101928450 ODF3L2 CDC34 HCN2 C2CD4C MIER2 FGF22 MISP
nsv953938	Chr.19:355801 - 1104501 on Build GRCh38	Deletion	PRTN3 ELANE CNN2 BSG GRIN3B RNF126 POLR2E CFD AZU1 PRSS57 LOC105372235 PALM GZMM RNU6-2 TPGS1 LOC101928450 PLPPR3 ODF3L2 HCN2 C2CD4C MED16 FGF22 MISP TMEM259 ARID3A POLRMT ABCA7 PTBP1 KISS1R MIR3187 ARHGAP45 THEG GPX4 SHC2 MADCAM1 FSTL3 RNU6-9 WDR18 MIR4745 R3HDM4 CDC34
nsv470101	Chr.19:401714 - 1008505 on Build GRCh38	Loss	PRTN3 ELANE BSG GRIN3B RNF126 CFD AZU1 PRSS57 LOC105372235 PALM GZMM TPGS1 LOC101928450 PLPPR3 ODF3L2 HCN2 C2CD4C MED16 FGF22 MISP ARID3A POLRMT PTBP1 KISS1R MIR3187 SHC2 MADCAM1 FSTL3 RNU6-9 WDR18 MIR4745 R3HDM4 CDC34

More Information

Additional Information:

For this assay, SNP(s) [rs151127711] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

extracellular matrix glycoprotein

Gene Ontology Categories:

Process(es)

ossification
kidney development
hematopoietic progenitor cell differentiation
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
spermatogenesis
male gonad development
positive regulation of cell-cell adhesion
lung development
adrenal gland development
negative regulation of BMP signaling pathway
negative regulation of activin receptor signaling pathway
negative regulation of osteoclast differentiation
positive regulation of transcription from RNA polymerase II promoter
cellular response to metal ion
negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

Function(s)

fibronectin binding
protein binding
activin binding