Hs04029526_cn

• Gene Symbol: MED25
• Assay Reference Genome Location: Chr.19:49839443 on build GRCh38
• Cytoband: 19q13.33

Target Gene Details

• Entrez Gene ID: 81857
• Gene Name: mediator complex subunit 25
• Gene Aliases: ACID1, ARC92, BVSYS, CMT2B2, P78, PTOV2, TCBAP0758
• Location: Chr.19:49818279-49840384 on Build GRCh38
• Assay Gene Location: Within Exon 19

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MED25	XM_011527353.1	18	3065	XP_011525655.1

Target Gene Details

• Entrez Gene ID: 100506033
• Gene Name: PTOV1 antisense RNA 1
• Gene Aliases: -
• Location: Chr.19:49838645-49851676 on Build GRCh38
• Assay Gene Location: Within Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PTOV1-AS1	NR_040037.1	4	1351
	AK092213.1	3	2965

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv9739	Chr.19:47901840 - 50143063 on Build GRCh38	Gain+Loss	SNAR-A12 CARD8-AS1 SNORD32A MIR4751 KDELR1 MIR4750 PRMT1 CYTH2 NOSIP C19orf73 SLC6A16 SNAR-A10 RUVBL2 SPHK2 SNAR-A7 CABP5 SNAR-A11 SNAR-A9 CD37 SCAF1 CA11 SNAR-A6 BCL2L12 NUCB1 MIR4749 LIN7B EMP3 GRIN2D CGB1 PNKP IL4I1 MIR6799 LOC105447645 SNAR-A5 RCN3 HRC KCNJ14 CGB5 SPACA4 RRAS PPP1R15A NUCB1-AS1 TBC1D17 GYS1 IZUMO1 NUP62 DKKL1 ADM5 SNAR-A13 PIH1D1 SEC1P SULT2B1 CCDC114 TEAD2 FGF21 MED25 ATF5 FLJ26850 SNAR-C5 TRPM4 VRK3 ZNF114 LOC100287477 SNRNP70 PRR12 SNAR-A14 SNORD34 FUT2 CCDC155 RPS11 PPFIA3 CGB2 SNAR-C1 SNORD35B C19orf68 SNAR-G2 ELSPBP1 SNAR-A8 LIG1 FTL TSKS LMTK3 CGB7 SNAR-D PTOV1-AS1 PTH2 BCAT2 FUT1 NTF4 HSD17B14 PLEKHA4 SNAR-C2 MIR150 LHB PTOV1-AS2 SNAR-C3 GFY ZNF473 RPL18 MIR6800 DBP MIR6798 LOC101928295 KCNA7 CGB8 PLA2G4C SNORD35A GRWD1 FCGRT SYNGR4 SNORD33 SIGLEC16 SNAR-A4 NTN5 ALDH16A1 LOC101059948 BAX SLC17A7 PLA2G4C-AS1 AP2A1 SIGLEC11 FAM83E IRF3 TULP2 SNAR-A3 CGB3 RASIP1 SNAR-A1 SNAR-B2 CARD8 PTOV1 SNAR-C4 LOC105372430 CPT1C SNAR-B1 MIR5088 FUZ RPL13A DHDH BSPH1 PRRG2 MIR4324 AKT1S1 TMEM143 SNAR-A2 SNAR-G1 FLT3LG MAMSTR
nsv470150	Chr.19:49618821 - 49856789 on Build GRCh38	Gain	BCL2L12 CPT1C PTOV1-AS1 PRR12 MIR5088 PRMT1 MIR4749 AP2A1 ADM5 FUZ IRF3 MIR6799 MED25 PTOV1-AS2 SCAF1 RRAS PTOV1 TSKS MIR6800
dgv53n68	Chr.19:49724393 - 49943224 on Build GRCh38	Loss	TBC1D17 MIR4751 PTOV1-AS1 MIR4750 NUP62 MIR4749 AP2A1 FUZ PNKP IL4I1 MIR6799 AKT1S1 MED25 PTOV1-AS2 ATF5 PTOV1 TSKS MIR6800
nsv953600	Chr.19:49555044 - 49938043 on Build GRCh38	Deletion	TBC1D17 MIR4751 PTOV1-AS1 MIR4750 NUP62 PRMT1 NOSIP AP2A1 ADM5 IRF3 MED25 PTOV1-AS2 SCAF1 ATF5 PTOV1 MIR6800 BCL2L12 CPT1C PRR12 MIR5088 MIR4749 FUZ PNKP PRRG2 IL4I1 MIR6799 AKT1S1 RRAS TSKS
nsv1160655	Chr.19:49489110 - 49841830 on Build GRCh38	Deletion	SNORD32A PTOV1-AS1 PRMT1 NOSIP AP2A1 ADM5 IRF3 MIR150 MED25 SCAF1 MIR6800 BCL2L12 CPT1C PRR12 MIR5088 SNORD34 FUZ RPL13A RPS11 SNORD35A PRRG2 SNORD35B MIR6799 FCGRT SNORD33 RCN3 RRAS TSKS

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

general transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
positive regulation of chromatin binding
positive regulation of transcription from RNA polymerase II promoter
negative regulation of fibroblast proliferation
positive regulation of cell cycle arrest
positive regulation of mediator complex assembly

Function(s)

protein binding
transcription factor binding
retinoic acid receptor binding
retinoid X receptor binding