Hs04030282_cn

• Gene Symbol: FSTL3
• Assay Reference Genome Location: Chr.19:679066 on build GRCh38
• Cytoband: 19p13.3

Target Gene Details

• Entrez Gene ID: 10272
• Gene Name: follistatin like 3
• Gene Aliases: FLRG, FSRP
• Location: Chr.19:676389-683392 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
FSTL3	NM_005860.2			NP_005851.1
	AK291958.1
	AK313341.1
	AY358917.1			AAQ89276.1
	BC005839.2			AAH05839.1
	BX439786.2
	U76702.1			AAC64321.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv578163	Chr.19:629303 - 682010 on Build GRCh38	Loss	FGF22 FSTL3 RNF126 POLRMT
dgv134n111	Chr.19:607984 - 967584 on Build GRCh38	Deletion	RNU6-9 PRSS57 LOC101928450 KISS1R MED16 PRTN3 PLPPR3 HCN2 AZU1 MIR4745 RNF126 POLRMT FGF22 ARID3A MISP MIR3187 FSTL3 PALM ELANE PTBP1 CFD R3HDM4
nsv428360	Chr.19:232069 - 702131 on Build GRCh38	Gain	C2CD4C PLPP2 PRSS57 MIER2 BSG HCN2 GZMM CDC34 RNF126 POLRMT FGF22 SHC2 LOC101929060 ODF3L2 FSTL3 MADCAM1 THEG TPGS1
nsv577978	Chr.19:294526 - 782854 on Build GRCh38	Gain	C2CD4C PRSS57 MIER2 LOC101928450 BSG HCN2 GZMM CDC34 RNF126 POLRMT FGF22 SHC2 MISP LOC101929060 ODF3L2 FSTL3 MADCAM1 THEG TPGS1 PALM
nsv953938	Chr.19:355801 - 1104501 on Build GRCh38	Deletion	RNU6-2 C2CD4C KISS1R MED16 PRTN3 PLPPR3 BSG GZMM CDC34 AZU1 CNN2 WDR18 ARHGAP45 POLRMT POLR2E TMEM259 LOC105372235 SHC2 MISP MIR3187 THEG TPGS1 PALM ELANE RNU6-9 PRSS57 LOC101928450 GRIN3B HCN2 MIR4745 RNF126 FGF22 GPX4 ARID3A ODF3L2 ABCA7 FSTL3 MADCAM1 PTBP1 CFD R3HDM4
nsv470101	Chr.19:401714 - 1008505 on Build GRCh38	Loss	C2CD4C KISS1R MED16 PRTN3 PLPPR3 BSG GZMM CDC34 AZU1 WDR18 POLRMT LOC105372235 SHC2 MISP MIR3187 TPGS1 PALM ELANE RNU6-9 PRSS57 LOC101928450 GRIN3B HCN2 MIR4745 RNF126 FGF22 ARID3A ODF3L2 FSTL3 MADCAM1 PTBP1 CFD R3HDM4

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

extracellular matrix glycoprotein

Gene Ontology Categories:

Process(es)

ossification
kidney development
hematopoietic progenitor cell differentiation
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
spermatogenesis
male gonad development
positive regulation of cell-cell adhesion
lung development
adrenal gland development
negative regulation of BMP signaling pathway
negative regulation of activin receptor signaling pathway
negative regulation of osteoclast differentiation
positive regulation of transcription from RNA polymerase II promoter
cellular response to metal ion
negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

Function(s)

fibronectin binding
protein binding
activin binding