Hs04030767_cn

• Gene Symbol: FSTL3
• Assay Reference Genome Location: Chr.19:677097 on build GRCh38
• Cytoband: 19p13.3

Target Gene Details

• Entrez Gene ID: 10272
• Gene Name: follistatin like 3
• Gene Aliases: FLRG, FSRP
• Location: Chr.19:676389-683392 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
FSTL3	NM_005860.2			NP_005851.1
	AK291958.1
	AK313341.1
	AY358917.1			AAQ89276.1
	BC005839.2			AAH05839.1
	BX439786.2
	U76702.1			AAC64321.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv578163	Chr.19:629303 - 682010 on Build GRCh38	Loss	POLRMT FGF22 RNF126 FSTL3
nsv428360	Chr.19:232069 - 702131 on Build GRCh38	Gain	POLRMT PLPP2 BSG FGF22 MADCAM1 CDC34 PRSS57 FSTL3 SHC2 ODF3L2 GZMM MIER2 C2CD4C RNF126 TPGS1 LOC101929060 HCN2 THEG
dgv134n111	Chr.19:607984 - 967584 on Build GRCh38	Deletion	POLRMT FGF22 RNU6-9 ELANE AZU1 PRSS57 CFD FSTL3 PLPPR3 MIR3187 MISP LOC101928450 PTBP1 MED16 PALM MIR4745 KISS1R PRTN3 RNF126 HCN2 R3HDM4 ARID3A
nsv577978	Chr.19:294526 - 782854 on Build GRCh38	Gain	POLRMT BSG FGF22 MADCAM1 CDC34 PRSS57 FSTL3 MISP LOC101928450 SHC2 ODF3L2 GZMM MIER2 PALM C2CD4C RNF126 TPGS1 LOC101929060 HCN2 THEG
nsv953938	Chr.19:355801 - 1104501 on Build GRCh38	Deletion	BSG FGF22 RNU6-9 ELANE RNU6-2 PRSS57 CFD FSTL3 LOC101928450 SHC2 LOC105372235 PTBP1 MED16 PALM TMEM259 KISS1R TPGS1 R3HDM4 GRIN3B ABCA7 WDR18 POLRMT ARHGAP45 MADCAM1 AZU1 CNN2 CDC34 PLPPR3 MIR3187 MISP ODF3L2 GZMM MIR4745 POLR2E C2CD4C PRTN3 RNF126 HCN2 GPX4 ARID3A THEG
nsv470101	Chr.19:401714 - 1008505 on Build GRCh38	Loss	BSG FGF22 RNU6-9 ELANE PRSS57 CFD FSTL3 LOC101928450 SHC2 LOC105372235 PTBP1 MED16 PALM KISS1R TPGS1 R3HDM4 GRIN3B WDR18 POLRMT MADCAM1 AZU1 CDC34 PLPPR3 MIR3187 MISP ODF3L2 GZMM MIR4745 C2CD4C PRTN3 RNF126 HCN2 ARID3A

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

extracellular matrix glycoprotein

Gene Ontology Categories:

Process(es)

ossification
kidney development
hematopoietic progenitor cell differentiation
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
spermatogenesis
male gonad development
positive regulation of cell-cell adhesion
lung development
adrenal gland development
negative regulation of BMP signaling pathway
negative regulation of activin receptor signaling pathway
negative regulation of osteoclast differentiation
positive regulation of transcription from RNA polymerase II promoter
cellular response to metal ion
negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

Function(s)

fibronectin binding
protein binding
activin binding