Hs04045733_cn

• Gene Symbol: MAPRE1
• Assay Reference Genome Location: Chr.20:32842891 on build GRCh38
• Cytoband: 20q11.21

Target Gene Details

• Entrez Gene ID: 22919
• Gene Name: microtubule associated protein RP/EB family member 1
• Gene Aliases: EB1
• Location: Chr.20:32819780-32850405 on Build GRCh38
• Assay Gene Location: Within Intron 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MAPRE1	NM_012325.2			NP_036457.1
	XM_011528696.2			XP_011526998.1
	AK297273.1
	AK310817.1
	AK312590.1
	BC106068.1			AAI06069.1
	BC109281.3			AAI09282.1
	U24166.1			AAC09471.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1056411	Chr.20:32469234 - 33355029 on Build GRCh38	Loss	SUN5 C20orf203 EFCAB8 COMMD7 BPIFA4P LOC101929698 BPIFA1 BPIFA2 LOC105372714 MAPRE1 BPIFB1 BPIFB4 LOC149950 BPIFB2 NOL4L BPIFA3 BPIFB3 BPIFB6 DNMT3B
nsv833959	Chr.20:32829604 - 32982934 on Build GRCh38	Loss	EFCAB8 MAPRE1
nsv179907	Chr.20:32835381 - 32844456 on Build GRCh38	Deletion	MAPRE1
nsv833957	Chr.20:32755316 - 32907992 on Build GRCh38	Gain+Loss	EFCAB8 MAPRE1 DNMT3B

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-motor microtubule binding protein

Gene Ontology Categories:

Process(es)

G2/M transition of mitotic cell cycle
sister chromatid cohesion
mitotic nuclear division
cell proliferation
positive regulation of cell migration
negative regulation of microtubule polymerization
protein localization to microtubule
cell division
cell-cell adhesion
positive regulation of microtubule plus-end binding
negative regulation of microtubule binding

Function(s)

protein binding
protein C-terminus binding
identical protein binding
poly(A) RNA binding
microtubule plus-end binding
cadherin binding involved in cell-cell adhesion