Hs04051668_cn

• Gene Symbol: PTK6
• Assay Reference Genome Location: Chr.20:63535178 on build GRCh38
• Cytoband: 20q13.33

Target Gene Details

• Entrez Gene ID: 5753
• Gene Name: protein tyrosine kinase 6
• Gene Aliases: BRK
• Location: Chr.20:63528413-63537370 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PTK6	NM_001256358.1			NP_001243287.1
	NM_005975.3			NP_005966.1
	XM_017027982.1			XP_016883471.1
	AK301364.1
	AK301691.1
	AK315232.1
	BC035843.1			AAH35843.1
	DA762278.1
	X78549.1			CAA55295.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv953306	Chr.20:63151949 - 63571247 on Build GRCh38	Deletion	MIR3196 LOC100130587 YTHDF1 FNDC11 LOC107985425 EEF1A2 LOC102723788 FLJ16779 BIRC7 MIR124-3 PPDPF NKAIN4 COL20A1 ARFGAP1 HELZ2 MIR4326 SRMS CHRNA4 PTK6 KCNQ2 LOC100130152
nsv521734	Chr.20:63522433 - 63566995 on Build GRCh38	Loss	HELZ2 FNDC11 SRMS PTK6
nsv9825	Chr.20:62775470 - 63601330 on Build GRCh38	Gain	OGFR-AS1 GMEB2 LINC00029 LOC107985428 LOC102723788 FLJ16779 LINC01056 MIR124-3 MRGBP ARFGAP1 OGFR SRMS CHRNA4 LOC63930 LINC00659 GID8 MIR3196 LOC100130587 TCFL5 YTHDF1 SLC17A9 FNDC11 COL9A3 LOC107985425 HAR1A EEF1A2 BIRC7 HAR1B PPDPF NKAIN4 COL20A1 DIDO1 HELZ2 MIR4326 DPH3P1 PTK6 KCNQ2 BHLHE23 LOC100130152
nsv470563	Chr.20:63486715 - 63793308 on Build GRCh38	Loss	SLC2A4RG ARFRP1 GMEB2 TNFRSF6B LOC100505771 ZGPAT FNDC11 EEF1A2 PPDPF RTEL1 HELZ2 STMN3 SRMS RTEL1-TNFRSF6B PTK6 LIME1 ZBTB46
nsv834033	Chr.20:63421436 - 63554987 on Build GRCh38	Gain	FNDC11 SRMS EEF1A2 PTK6 KCNQ2 PPDPF
nsv834034	Chr.20:63462825 - 63625901 on Build GRCh38	Loss	GMEB2 HELZ2 FNDC11 SRMS EEF1A2 PTK6 KCNQ2 PPDPF
nsv586569	Chr.20:63496168 - 63548764 on Build GRCh38	Loss	SRMS EEF1A2 PTK6 PPDPF
esv2758806	Chr.20:63470996 - 63745014 on Build GRCh38	Gain+Loss	SLC2A4RG ARFRP1 GMEB2 TNFRSF6B LOC100505771 ZGPAT FNDC11 EEF1A2 PPDPF RTEL1 HELZ2 STMN3 SRMS RTEL1-TNFRSF6B PTK6 KCNQ2 LIME1 ZBTB46

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protein-binding activity modulator, scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

protein phosphorylation
transmembrane receptor protein tyrosine kinase signaling pathway
negative regulation of signal transduction
positive regulation of neuron projection development
cell migration
peptidyl-tyrosine autophosphorylation
ERBB2 signaling pathway
regulation of cell proliferation
tyrosine phosphorylation of Stat3 protein
tyrosine phosphorylation of Stat5 protein
positive regulation of tyrosine phosphorylation of Stat3 protein
innate immune response
positive regulation of epidermal growth factor receptor signaling pathway
positive regulation of cell cycle
negative regulation of growth
protein autophosphorylation
intestinal epithelial cell differentiation
negative regulation of protein tyrosine kinase activity
cellular response to retinoic acid

Function(s)

protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
receptor binding
protein binding
ATP binding
identical protein binding