Hs04053813_cn

• Gene Symbol: PTK6
• Assay Reference Genome Location: Chr.20:63535584 on build GRCh38
• Cytoband: 20q13.33

Target Gene Details

• Entrez Gene ID: 5753
• Gene Name: protein tyrosine kinase 6
• Gene Aliases: BRK
• Location: Chr.20:63528413-63537370 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PTK6	NM_001256358.1			NP_001243287.1
	NM_005975.3			NP_005966.1
	XM_017027982.1			XP_016883471.1
	AK301364.1
	AK301691.1
	AK315232.1
	BC035843.1			AAH35843.1
	DA762278.1
	X78549.1			CAA55295.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv953306	Chr.20:63151949 - 63571247 on Build GRCh38	Deletion	YTHDF1 FNDC11 COL20A1 MIR3196 CHRNA4 HELZ2 EEF1A2 LOC100130587 MIR124-3 ARFGAP1 PPDPF FLJ16779 LOC107985425 PTK6 SRMS KCNQ2 NKAIN4 LOC102723788 BIRC7 MIR4326 LOC100130152
dgv521n27	Chr.20:63522433 - 63566995 on Build GRCh38	Loss	FNDC11 PTK6 SRMS HELZ2
nsv9825	Chr.20:62775470 - 63601330 on Build GRCh38	Gain	YTHDF1 LOC63930 CHRNA4 HELZ2 OGFR-AS1 BHLHE23 EEF1A2 GMEB2 MIR124-3 LINC00659 MRGBP TCFL5 ARFGAP1 COL9A3 SRMS OGFR KCNQ2 LOC102723788 BIRC7 GID8 LOC100130152 LOC107985428 FNDC11 COL20A1 MIR3196 LOC100130587 PPDPF FLJ16779 LOC107985425 HAR1A PTK6 LINC00029 LINC01056 NKAIN4 MIR4326 DPH3P1 SLC17A9 DIDO1 HAR1B
nsv834033	Chr.20:63421436 - 63554987 on Build GRCh38	Gain	FNDC11 PTK6 SRMS KCNQ2 EEF1A2 PPDPF
nsv470563	Chr.20:63486715 - 63793308 on Build GRCh38	Loss	FNDC11 STMN3 LOC100505771 RTEL1-TNFRSF6B HELZ2 EEF1A2 GMEB2 SLC2A4RG PPDPF PTK6 SRMS ZBTB46 RTEL1 LIME1 ZGPAT TNFRSF6B ARFRP1
nsv834034	Chr.20:63462825 - 63625901 on Build GRCh38	Loss	FNDC11 PTK6 SRMS KCNQ2 HELZ2 EEF1A2 GMEB2 PPDPF
nsv586569	Chr.20:63496168 - 63548764 on Build GRCh38	Loss	PTK6 SRMS EEF1A2 PPDPF
esv2758806	Chr.20:63470996 - 63745014 on Build GRCh38	Gain+Loss	FNDC11 STMN3 LOC100505771 RTEL1-TNFRSF6B HELZ2 EEF1A2 GMEB2 SLC2A4RG PPDPF PTK6 SRMS ZBTB46 RTEL1 KCNQ2 LIME1 ZGPAT TNFRSF6B ARFRP1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protein-binding activity modulator, scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

protein phosphorylation
transmembrane receptor protein tyrosine kinase signaling pathway
negative regulation of signal transduction
positive regulation of neuron projection development
cell migration
peptidyl-tyrosine autophosphorylation
ERBB2 signaling pathway
regulation of cell proliferation
tyrosine phosphorylation of Stat3 protein
tyrosine phosphorylation of Stat5 protein
positive regulation of tyrosine phosphorylation of Stat3 protein
innate immune response
positive regulation of epidermal growth factor receptor signaling pathway
positive regulation of cell cycle
negative regulation of growth
protein autophosphorylation
intestinal epithelial cell differentiation
negative regulation of protein tyrosine kinase activity
cellular response to retinoic acid

Function(s)

protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
receptor binding
protein binding
ATP binding
identical protein binding