Hs04086461_cn

• Gene Symbol: ADORA2A
• Assay Reference Genome Location: Chr.22:24424974 on build GRCh38
• Cytoband: 22q11.23

Target Gene Details

• Entrez Gene ID: 135
• Gene Name: adenosine A2a receptor
• Gene Aliases: A2aR, ADORA2, RDC8
• Location: Chr.22:24423597-24442360 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ADORA2A	NM_001278500.1			NP_001265429.1
	DA781734.1
	EU036694.1

Target Gene Details

• Entrez Gene ID: 101730217
• Gene Name: SPECC1L-ADORA2A readthrough (NMD candidate)
• Gene Aliases: -
• Location: Chr.22:24270817-24442360 on Build GRCh38
• Assay Gene Location: Within Intron 18

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SPECC1L-ADORA2A	NR_103546.1
	AB209022.1			BAD92259.1
	GR939218.1
	GR939229.1
	GR939241.1
	GR939262.1
	GR939274.1
	GR939286.1
	GR939298.1
	GR939310.1
	GR939322.1
	GR939334.1
	GR939358.1
	GR939370.1
	GR939382.1
	GR939394.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2724068	Chr.22:24288741 - 24669870 on Build GRCh38	Deletion	SNRPD3 GUCD1 BCRP3 UPB1 GGT1 LRRC75B ADORA2A-AS1 SPECC1L-ADORA2A SPECC1L POM121L10P ADORA2A
dgv8039n54	Chr.22:23323169 - 24601506 on Build GRCh38	Gain	MIF CABIN1 SNRPD3 GUCD1 DERL3 LRRC75B SMARCB1 PCAT14 SLC2A11 GSTT2 C22orf15 POM121L9P IGLL1 LOC101929374 RGL4 GGT5 MIF-AS1 DRICH1 LOC107985555 GUSBP11 ZNF70 VPREB3 ADORA2A-AS1 LOC388882 GSTT2B CHCHD10 MMP11 DDT CES5AP1 UPB1 GSTTP1 GGT1 LOC107985559 ZDHHC8P1 SPECC1L-ADORA2A SPECC1L SUSD2 LOC100652871 DDTL ADORA2A
nsv1055830	Chr.22:24005071 - 24643213 on Build GRCh38	Gain	CABIN1 SNRPD3 GUCD1 LRRC75B ADORA2A-AS1 POM121L9P BCRP3 UPB1 GSTTP1 GGT1 GGT5 SPECC1L-ADORA2A SPECC1L SUSD2 ADORA2A
nsv588744	Chr.22:24285587 - 24617379 on Build GRCh38	Gain	SNRPD3 GUCD1 UPB1 GGT1 LRRC75B ADORA2A-AS1 SPECC1L-ADORA2A SPECC1L ADORA2A
nsv9884	Chr.22:24415625 - 24662249 on Build GRCh38	Gain+Loss	SNRPD3 GUCD1 BCRP3 UPB1 GGT1 LRRC75B ADORA2A-AS1 SPECC1L-ADORA2A SPECC1L POM121L10P ADORA2A
nsv834160	Chr.22:24329972 - 24507687 on Build GRCh38	Gain	UPB1 ADORA2A-AS1 SPECC1L-ADORA2A SPECC1L ADORA2A
nsv1057819	Chr.22:24290518 - 24624081 on Build GRCh38	Gain	SNRPD3 GUCD1 UPB1 GGT1 LRRC75B ADORA2A-AS1 SPECC1L-ADORA2A SPECC1L ADORA2A
nsv526567	Chr.22:23348138 - 24600663 on Build GRCh38	Gain	MIF CABIN1 SNRPD3 GUCD1 DERL3 LRRC75B SMARCB1 PCAT14 SLC2A11 GSTT2 C22orf15 POM121L9P IGLL1 LOC101929374 RGL4 GGT5 MIF-AS1 DRICH1 LOC107985555 GUSBP11 ZNF70 VPREB3 ADORA2A-AS1 LOC388882 GSTT2B CHCHD10 MMP11 DDT CES5AP1 UPB1 GSTTP1 GGT1 LOC107985559 ZDHHC8P1 SPECC1L-ADORA2A SPECC1L SUSD2 LOC100652871 DDTL ADORA2A
esv2724041	Chr.22:23315914 - 24669376 on Build GRCh38	Deletion	MIF CABIN1 SNRPD3 GUCD1 DERL3 LRRC75B SMARCB1 PCAT14 SLC2A11 GSTT2 C22orf15 POM121L9P IGLL1 BCR LOC101929374 RGL4 GGT5 MIF-AS1 DRICH1 LOC107985555 GUSBP11 ZNF70 VPREB3 ADORA2A-AS1 LOC388882 GSTT2B CHCHD10 MMP11 DDT BCRP3 CES5AP1 UPB1 GSTTP1 GGT1 LOC107985559 ZDHHC8P1 SPECC1L-ADORA2A SPECC1L POM121L10P SUSD2 LOC100652871 DDTL ADORA2A
esv3893463	Chr.22:24009046 - 24601506 on Build GRCh38	Gain	CABIN1 SNRPD3 GUCD1 LRRC75B ADORA2A-AS1 POM121L9P UPB1 GGT1 GGT5 SPECC1L-ADORA2A SPECC1L SUSD2 ADORA2A
dgv4528n100	Chr.22:23322244 - 24682765 on Build GRCh38	Gain	MIF CABIN1 SNRPD3 GUCD1 DERL3 LRRC75B SMARCB1 PCAT14 SLC2A11 GSTT2 C22orf15 POM121L9P IGLL1 LOC101929374 RGL4 GGT5 MIF-AS1 DRICH1 LOC107985555 GUSBP11 ZNF70 VPREB3 ADORA2A-AS1 LOC388882 GSTT2B CHCHD10 MMP11 DDT BCRP3 CES5AP1 UPB1 GSTTP1 GGT1 LOC107985559 ZDHHC8P1 SPECC1L-ADORA2A SPECC1L POM121L10P SUSD2 LOC100652871 DDTL ADORA2A
nsv953061	Chr.22:24410533 - 24427132 on Build GRCh38	Deletion	SPECC1L-ADORA2A SPECC1L ADORA2A
esv3575443	Chr.22:23348201 - 24670505 on Build GRCh38	Gain	MIF CABIN1 SNRPD3 GUCD1 DERL3 LRRC75B SMARCB1 PCAT14 SLC2A11 GSTT2 C22orf15 POM121L9P IGLL1 LOC101929374 RGL4 GGT5 MIF-AS1 DRICH1 LOC107985555 GUSBP11 ZNF70 VPREB3 ADORA2A-AS1 LOC388882 GSTT2B CHCHD10 MMP11 DDT BCRP3 CES5AP1 UPB1 GSTTP1 GGT1 LOC107985559 ZDHHC8P1 SPECC1L-ADORA2A SPECC1L POM121L10P SUSD2 LOC100652871 DDTL ADORA2A

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

G-protein coupled receptor

Gene Ontology Categories:

Process(es)

adenosine receptor signaling pathway
cAMP biosynthetic process
phagocytosis
apoptotic process
inflammatory response
cellular defense response
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
cell-cell signaling
central nervous system development
blood coagulation
sensory perception
blood circulation
positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
cellular protein metabolic process

Function(s)

G-protein coupled adenosine receptor activity
protein binding
enzyme binding
identical protein binding