Hs04087735_cn

• Gene Symbol: ADORA2A
• Assay Reference Genome Location: Chr.22:24425646 on build GRCh38
• Cytoband: 22q11.23

Target Gene Details

• Entrez Gene ID: 135
• Gene Name: adenosine A2a receptor
• Gene Aliases: A2aR, ADORA2, RDC8
• Location: Chr.22:24423597-24442360 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ADORA2A	NM_001278500.1			NP_001265429.1
	DA781734.1
	EU036694.1

Target Gene Details

• Entrez Gene ID: 101730217
• Gene Name: SPECC1L-ADORA2A readthrough (NMD candidate)
• Gene Aliases: -
• Location: Chr.22:24270817-24442360 on Build GRCh38
• Assay Gene Location: Within Intron 18

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SPECC1L-ADORA2A	NR_103546.1
	AB209022.1			BAD92259.1
	GR939218.1
	GR939229.1
	GR939241.1
	GR939262.1
	GR939274.1
	GR939286.1
	GR939298.1
	GR939310.1
	GR939322.1
	GR939334.1
	GR939358.1
	GR939370.1
	GR939382.1
	GR939394.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2724068	Chr.22:24288741 - 24669870 on Build GRCh38	Deletion	GUCD1 ADORA2A SNRPD3 UPB1 GGT1 BCRP3 SPECC1L-ADORA2A SPECC1L POM121L10P LRRC75B ADORA2A-AS1
dgv8039n54	Chr.22:23323169 - 24601506 on Build GRCh38	Gain	DRICH1 GSTT2B GGT1 LOC101929374 SMARCB1 GGT5 SPECC1L-ADORA2A MIF C22orf15 MIF-AS1 RGL4 LOC388882 ADORA2A-AS1 GUCD1 POM121L9P DDT GSTT2 PCAT14 DDTL MMP11 IGLL1 SLC2A11 LOC107985559 ADORA2A ZDHHC8P1 SNRPD3 CES5AP1 LOC107985555 DERL3 CABIN1 SUSD2 LOC100652871 CHCHD10 VPREB3 UPB1 GUSBP11 GSTTP1 SPECC1L LRRC75B ZNF70
nsv1055830	Chr.22:24005071 - 24643213 on Build GRCh38	Gain	ADORA2A SNRPD3 GGT1 GGT5 SPECC1L-ADORA2A CABIN1 SUSD2 ADORA2A-AS1 GUCD1 POM121L9P UPB1 BCRP3 GSTTP1 SPECC1L LRRC75B
nsv588744	Chr.22:24285587 - 24617379 on Build GRCh38	Gain	GUCD1 ADORA2A SNRPD3 UPB1 GGT1 SPECC1L-ADORA2A SPECC1L LRRC75B ADORA2A-AS1
nsv9884	Chr.22:24415625 - 24662249 on Build GRCh38	Gain+Loss	GUCD1 ADORA2A SNRPD3 UPB1 GGT1 BCRP3 SPECC1L-ADORA2A SPECC1L POM121L10P LRRC75B ADORA2A-AS1
nsv834160	Chr.22:24329972 - 24507687 on Build GRCh38	Gain	ADORA2A UPB1 SPECC1L-ADORA2A SPECC1L ADORA2A-AS1
nsv1057819	Chr.22:24290518 - 24624081 on Build GRCh38	Gain	GUCD1 ADORA2A SNRPD3 UPB1 GGT1 SPECC1L-ADORA2A SPECC1L LRRC75B ADORA2A-AS1
nsv526567	Chr.22:23348138 - 24600663 on Build GRCh38	Gain	DRICH1 GSTT2B GGT1 LOC101929374 SMARCB1 GGT5 SPECC1L-ADORA2A MIF C22orf15 MIF-AS1 RGL4 LOC388882 ADORA2A-AS1 GUCD1 POM121L9P DDT GSTT2 PCAT14 DDTL MMP11 IGLL1 SLC2A11 LOC107985559 ADORA2A ZDHHC8P1 SNRPD3 CES5AP1 LOC107985555 DERL3 CABIN1 SUSD2 LOC100652871 CHCHD10 VPREB3 UPB1 GUSBP11 GSTTP1 SPECC1L LRRC75B ZNF70
esv2724041	Chr.22:23315914 - 24669376 on Build GRCh38	Deletion	DRICH1 GSTT2B GGT1 LOC101929374 SMARCB1 GGT5 SPECC1L-ADORA2A MIF POM121L10P C22orf15 MIF-AS1 RGL4 LOC388882 ADORA2A-AS1 GUCD1 POM121L9P DDT GSTT2 PCAT14 DDTL MMP11 IGLL1 SLC2A11 LOC107985559 ADORA2A ZDHHC8P1 SNRPD3 CES5AP1 LOC107985555 DERL3 CABIN1 SUSD2 LOC100652871 CHCHD10 VPREB3 UPB1 BCRP3 BCR GUSBP11 GSTTP1 SPECC1L LRRC75B ZNF70
esv3893463	Chr.22:24009046 - 24601506 on Build GRCh38	Gain	ADORA2A SNRPD3 GGT1 GGT5 SPECC1L-ADORA2A CABIN1 SUSD2 ADORA2A-AS1 GUCD1 POM121L9P UPB1 SPECC1L LRRC75B
dgv4528n100	Chr.22:23322244 - 24682765 on Build GRCh38	Gain	DRICH1 GSTT2B GGT1 LOC101929374 SMARCB1 GGT5 SPECC1L-ADORA2A MIF POM121L10P C22orf15 MIF-AS1 RGL4 LOC388882 ADORA2A-AS1 GUCD1 POM121L9P DDT GSTT2 PCAT14 DDTL MMP11 IGLL1 SLC2A11 LOC107985559 ADORA2A ZDHHC8P1 SNRPD3 CES5AP1 LOC107985555 DERL3 CABIN1 SUSD2 LOC100652871 CHCHD10 VPREB3 UPB1 BCRP3 GUSBP11 GSTTP1 SPECC1L LRRC75B ZNF70
nsv953061	Chr.22:24410533 - 24427132 on Build GRCh38	Deletion	ADORA2A SPECC1L-ADORA2A SPECC1L
esv3575443	Chr.22:23348201 - 24670505 on Build GRCh38	Gain	DRICH1 GSTT2B GGT1 LOC101929374 SMARCB1 GGT5 SPECC1L-ADORA2A MIF POM121L10P C22orf15 MIF-AS1 RGL4 LOC388882 ADORA2A-AS1 GUCD1 POM121L9P DDT GSTT2 PCAT14 DDTL MMP11 IGLL1 SLC2A11 LOC107985559 ADORA2A ZDHHC8P1 SNRPD3 CES5AP1 LOC107985555 DERL3 CABIN1 SUSD2 LOC100652871 CHCHD10 VPREB3 UPB1 BCRP3 GUSBP11 GSTTP1 SPECC1L LRRC75B ZNF70

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

G-protein coupled receptor

Gene Ontology Categories:

Process(es)

adenosine receptor signaling pathway
cAMP biosynthetic process
phagocytosis
apoptotic process
inflammatory response
cellular defense response
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
cell-cell signaling
central nervous system development
blood coagulation
sensory perception
blood circulation
positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
cellular protein metabolic process

Function(s)

G-protein coupled adenosine receptor activity
protein binding
enzyme binding
identical protein binding