Hs04239866_cn

• Gene Symbol: PTPN18
• Assay Reference Genome Location: Chr.2:130358059 on build GRCh38
• Cytoband: 2q21.1

Target Gene Details

• Entrez Gene ID: 26469
• Gene Name: protein tyrosine phosphatase, non-receptor type 18
• Gene Aliases: BDP1, PTP-HSCF
• Location: Chr.2:130356007-130375409 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PTPN18	NM_001142370.1			NP_001135842.1
	NM_014369.3			NP_055184.2
	XM_006712416.3			XP_006712479.1
	XM_006712417.1			XP_006712480.1
	XM_017003798.1			XP_016859287.1
	AK303804.1
	BC024280.1			AAH24280.1
	BC041562.1			AAH41562.1
	BC052800.1			AAH52800.1
	BI261717.1
	DN995571.1
	X79568.1			CAA56105.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv998333	Chr.2:130059754 - 130454126 on Build GRCh38	Gain+Loss	CCDC115 POTEF NOC2LP1 PTPN18 MED15P9 FAR2P2 MZT2B SMPD4 IMP4 CYP4F62P CCDC74B TUBA3E
esv2760631	Chr.2:130005319 - 130400286 on Build GRCh38	Gain+Loss	CCDC115 FAR2P1 POTEF NOC2LP1 PTPN18 MED15P9 MZT2B SMPD4 IMP4 CCDC74B TUBA3E
nsv583133	Chr.2:130281566 - 130390535 on Build GRCh38	Loss	CCDC115 PTPN18 IMP4
dgv7079n54	Chr.2:130181715 - 130391244 on Build GRCh38	Loss	CCDC115 NOC2LP1 PTPN18 MZT2B SMPD4 IMP4 TUBA3E
esv3584065	Chr.2:130046530 - 130400286 on Build GRCh38	Loss	CCDC115 FAR2P1 POTEF NOC2LP1 PTPN18 MED15P9 MZT2B SMPD4 IMP4 CCDC74B TUBA3E
nsv583113	Chr.2:130132813 - 130369588 on Build GRCh38	Gain	CCDC115 NOC2LP1 PTPN18 MED15P9 MZT2B SMPD4 IMP4 CCDC74B TUBA3E
nsv520559	Chr.2:130133334 - 130390535 on Build GRCh38	Gain+Loss	CCDC115 NOC2LP1 PTPN18 MED15P9 MZT2B SMPD4 IMP4 CCDC74B TUBA3E
nsv1005664	Chr.2:130159287 - 130649604 on Build GRCh38	Loss	CCDC115 NOC2LP1 POTEI PTPN18 FAR2P2 MZT2B CYP4F62P LOC646743 POTEJ TUBA3E CFC1 TISP43 LOC107985778 CFC1B SMPD4 IMP4
esv2763387	Chr.2:130026123 - 130400286 on Build GRCh38	Loss	CCDC115 FAR2P1 POTEF NOC2LP1 PTPN18 MED15P9 MZT2B SMPD4 IMP4 CCDC74B TUBA3E
dgv7080n54	Chr.2:130185940 - 130390535 on Build GRCh38	Gain	CCDC115 NOC2LP1 PTPN18 MZT2B IMP4 TUBA3E
nsv459274	Chr.2:128746961 - 130390535 on Build GRCh38	Loss	RAB6C CCDC115 FAR2P1 RAB6C-AS1 NOC2LP1 PTPN18 MED15P9 LOC101927924 MZT2B TUBA3E LOC151121 POTEF LOC101927881 LOC389033 SMPD4 IMP4 CCDC74B
dgv7083n54	Chr.2:130236250 - 130440530 on Build GRCh38	Loss	CCDC115 PTPN18 FAR2P2 IMP4 CYP4F62P
esv3592451	Chr.2:130282861 - 130401532 on Build GRCh38	Gain	CCDC115 PTPN18 IMP4
nsv583132	Chr.2:130255764 - 130390535 on Build GRCh38	Gain	CCDC115 PTPN18 IMP4
esv2751826	Chr.2:129606158 - 130385563 on Build GRCh38	Gain	RAB6C CCDC115 FAR2P1 RAB6C-AS1 NOC2LP1 PTPN18 MED15P9 LOC101927924 MZT2B TUBA3E POTEF LOC389033 SMPD4 IMP4 CCDC74B
nsv1001073	Chr.2:130290533 - 130400286 on Build GRCh38	Gain	CCDC115 PTPN18 IMP4
esv2759092	Chr.2:129589265 - 132440430 on Build GRCh38	Gain+Loss	C2orf27A FAR2P1 ZNF806 GPR39 RAB6C-AS1 WTH3DI FAM168B AMER3 TUBA3E CFC1 LOC150776 LOC107985778 NOC2LP2 FAM201B SMPD4 IMP4 TUBA3D NOC2LP1 PTPN18 MED15P9 MZT2B TISP43 MZT2A LOC100507460 C2orf27B LOC389033 GPR148 CCDC74B MIR663B LOC440910 POTEKP POTEI CCDC74A CFC1B CYP4F30P RAB6C CCDC115 ARHGEF4 MIR4784 FAR2P2 LOC101927924 CYP4F62P LOC646743 POTEJ POTEE LINC01087 POTEF LINC01120 ANKRD30BL PLEKHB2
esv3893326	Chr.2:130080351 - 130492798 on Build GRCh38	Gain	CCDC115 NOC2LP1 POTEI PTPN18 MED15P9 FAR2P2 MZT2B CYP4F62P TUBA3E POTEF SMPD4 IMP4 CCDC74B
dgv4073n100	Chr.2:130091652 - 130400286 on Build GRCh38	Gain	CCDC115 POTEF NOC2LP1 PTPN18 MED15P9 MZT2B SMPD4 IMP4 CCDC74B TUBA3E
nsv428403	Chr.2:129818076 - 130882067 on Build GRCh38	Loss	FAR2P1 RAB6C-AS1 POTEI AMER3 TUBA3E CFC1 LOC107985778 CFC1B SMPD4 IMP4 CYP4F30P RAB6C CCDC115 ARHGEF4 NOC2LP1 PTPN18 MED15P9 FAR2P2 LOC101927924 MZT2B CYP4F62P LOC646743 POTEJ TISP43 POTEF LOC389033 GPR148 CCDC74B

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

protein dephosphorylation
peptidyl-tyrosine dephosphorylation

Function(s)

non-membrane spanning protein tyrosine phosphatase activity
protein binding