Hs04274263_cn

• Gene Symbol: CISD2
• Assay Reference Genome Location: Chr.4:102872562 on build GRCh38
• Cytoband: 4q24

Target Gene Details

• Entrez Gene ID: 493856
• Gene Name: CDGSH iron sulfur domain 2
• Gene Aliases: ERIS, Miner1, NAF-1, WFS2, ZCD2
• Location: Chr.4:102868978-102892807 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CISD2	NM_001008388.4			NP_001008389.1
	AK292134.1
	BC032300.1			AAH32300.1
	BX537971.1			CAD97935.1
	DN993861.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2759270	Chr.4:102859548 - 103136164 on Build GRCh38	Gain	UBE2D3 BDH2 CENPE SLC9B1 CISD2 SLC9B2
nsv594957	Chr.4:102806853 - 102948934 on Build GRCh38	Loss	UBE2D3 LOC105377348 SLC9B1 CISD2

More Information

Additional Information:

For this assay, SNP(s) [rs79069143] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

mitophagy
multicellular organism aging
regulation of autophagy

Function(s)

protein binding
protein homodimerization activity
poly(A) RNA binding
metal ion binding
2 iron, 2 sulfur cluster binding