Hs04341946_cn

• Gene Symbol: YWHAG
• Assay Reference Genome Location: Chr.7:76349545 on build GRCh38
• Cytoband: 7q11.23

Target Gene Details

• Entrez Gene ID: 7532
• Gene Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
• Gene Aliases: 14-3-3GAMMA, PPP1R170
• Location: Chr.7:76326791-76359025 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
YWHAG	NM_012479.3			NP_036611.2
	AB024334.1			BAA85184.1
	AF142498.1			AAD48408.1
	AK024230.1
	AK293505.1
	AK295029.1
	BC020963.2			AAH20963.1
	CR541904.1			CAG46702.1
	CR541925.1			CAG46723.1
	DC343104.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2422494	Chr.7:76286900 - 76984449 on Build GRCh38	Duplication	HSPB1 POMZP3 SPDYE16 ZP3 DTX2 FDPSP2 SRRM3 SSC4D LOC100133091 YWHAG DTX2P1-UPK3BP1-PMS2P11 LOC105375355
nsv528969	Chr.7:75074053 - 76920728 on Build GRCh38	Gain	MIR4651 NCF1C ZP3 DTX2 NSUN5P1 SSC4D HIP1 STYXL1 LOC441259 PMS2P10 POR YWHAG LOC105375355 LOC107986711 RHBDD2 POMZP3 GTF2IRD2B CCL26 SRRM3 GTF2IP7 SPDYE5 POM121C PMS2P3 SNORA14A SPDYE16 TMEM120A MDH2 STAG3L1 HSPB1 FDPSP2 TRIM73 PMS2P2 LOC541473 GTF2IP1 LOC100133091 CCL24
nsv428174	Chr.7:76305019 - 77220062 on Build GRCh38	Gain	SPDYE16 ZP3 DTX2 CCDC146 SSC4D SPDYE17 YWHAG LOC105375355 POMZP3 FGL2 PMS2P9 SPDYE18 FDPSP2 LOC100133091 DTX2P1-UPK3BP1-PMS2P11
nsv1028665	Chr.7:76336044 - 76445651 on Build GRCh38	Gain	ZP3 SSC4D YWHAG
dgv120n16	Chr.7:75440769 - 76641919 on Build GRCh38	Deletion	MIR4651 ZP3 DTX2 SSC4D HIP1 STYXL1 POR YWHAG LOC105375355 LOC107986711 RHBDD2 POMZP3 CCL26 SRRM3 GTF2IP7 SPDYE5 POM121C PMS2P3 SNORA14A SPDYE16 TMEM120A MDH2 HSPB1 FDPSP2 LOC100133091 CCL24

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

G2/M transition of mitotic cell cycle
negative regulation of protein kinase activity
protein targeting
regulation of signal transduction
cellular response to insulin stimulus
regulation of neuron differentiation
regulation of synaptic plasticity
membrane organization
negative regulation of protein serine/threonine kinase activity
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

Function(s)

protein kinase C binding
insulin-like growth factor receptor binding
protein binding
protein kinase C inhibitor activity
protein domain specific binding
receptor tyrosine kinase binding
poly(A) RNA binding