Hs04369269_cn

• Gene Symbol: MIR4479
• Assay Reference Genome Location: Chr.9:136886759 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 100616480
• Gene Name: microRNA 4479
• Gene Aliases: -
• Location: Chr.9:136886733-136886803 on Build GRCh38
• Assay Gene Location:

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MIR4479	NR_039697.1

Target Gene Details

• Entrez Gene ID: 7186
• Gene Name: TNF receptor associated factor 2
• Gene Aliases: MGC:45012, TRAP, TRAP3
• Location: Chr.9:136881776-136926615 on Build GRCh38
• Assay Gene Location: Within Intron 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRAF2	NM_021138.3			NP_066961.2
	XM_011518973.2			XP_011517275.1
	XM_011518976.2			XP_011517278.1
	XM_011518977.2			XP_011517279.1
	AK054686.1			BAB70792.1
	AK222961.1
	AK289722.1
	AK294607.1
	AK298370.1
	BC033810.1			AAH33810.1
	BC043492.1			AAH43492.1
	BM785733.1
	BX538160.1			CAD98040.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv951205	Chr.9:136821949 - 136944648 on Build GRCh38	Deletion	PHPT1 MAMDC4 C9orf172 RABL6 FBXW5 MIR4292 TRAF2 EDF1 MIR4479
nsv818738	Chr.9:136740043 - 137009585 on Build GRCh38	Gain	MIR6722 RABL6 LCN10 FBXW5 MIR4292 LCN6 CCDC183-AS1 MAMDC4 LCN8 PRR31 C9orf142 LCN15 PHPT1 C8G CLIC3 LCN12 CCDC183 TRAF2 EDF1 LCNL1 ABCA2 C9orf172 PTGDS TMEM141 MIR4479 LOC100128593
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	NELFB NDOR1 FBXW5 SAPCD2 CCDC183-AS1 C9orf139 MIR3621 DPP7 GRIN1 PRR31 TMEM210 PHPT1 CLIC3 MIR7114 TRAF2 LCNL1 RNF208 FUT7 CYSRT1 TUBB4B NSMF LRRC26 MIR4479 RABL6 MIR4292 MAN1B1-AS1 MAMDC4 ANAPC2 STPG3 MAN1B1 TOR4A NOXA1 ENTPD8 NRARP C9orf142 EXD3 TMEM203 C8G FAM166A SLC34A3 LCN12 NPDC1 CCDC183 ENTPD2 SSNA1 EDF1 UAP1L1 PNPLA7 ABCA2 C9orf172 LOC101930307 PTGDS TPRN C9orf173-AS1 RNF224
esv2759720	Chr.9:136356377 - 136932033 on Build GRCh38	Loss	MIR6722 MIR4674 RABL6 LCN10 SDCCAG3 SNORA17A INPP5E MIR4292 HSPC324 MIR126 LCN6 CCDC183-AS1 MAMDC4 NOTCH1 LCN8 GPSM1 PMPCA LCN15 SNHG7 SNORA17B PHPT1 EGFL7 C9orf163 MIR4673 CCDC183 TRAF2 EDF1 SEC16A SNAPC4 LINC01451 C9orf172 CARD9 NALT1 TMEM141 DNLZ FAM69B MIR4479 AGPAT2 LOC100128593
nsv469918	Chr.9:136359865 - 137173890 on Build GRCh38	Loss	MIR4674 FBXW5 INPP5E HSPC324 MIR126 SAPCD2 CCDC183-AS1 C9orf139 NOTCH1 MIR3621 LCN8 DPP7 GRIN1 PRR31 TMEM210 SNORA17B PHPT1 EGFL7 CLIC3 C9orf163 TRAF2 LCNL1 SEC16A SNAPC4 FUT7 LRRC26 MIR4479 AGPAT2 MIR6722 RABL6 LCN10 SDCCAG3 SNORA17A MIR4292 MAN1B1-AS1 LCN6 MAMDC4 MAN1B1 PMPCA C9orf142 LCN15 SNHG7 C8G MIR4673 LCN12 NPDC1 CCDC183 ENTPD2 EDF1 UAP1L1 ABCA2 LINC01451 C9orf172 CARD9 LOC101930307 PTGDS NALT1 TMEM141 DNLZ FAM69B LOC100128593
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	NELFB NDOR1 FBXW5 HSPC324 MIR126 SAPCD2 CCDC183-AS1 C9orf139 MIR3621 LCN8 DPP7 GRIN1 PRR31 TMEM210 SNORA17B PHPT1 EGFL7 CLIC3 TRAF2 LCNL1 RNF208 FUT7 CYSRT1 TUBB4B LRRC26 MIR4479 AGPAT2 MIR6722 RABL6 LCN10 SNORA17A MIR4292 MAN1B1-AS1 LCN6 MAMDC4 ANAPC2 STPG3 MAN1B1 TOR4A NRARP C9orf142 LCN15 EXD3 SNHG7 TMEM203 C8G FAM166A SLC34A3 LCN12 NPDC1 CCDC183 ENTPD2 SSNA1 EDF1 UAP1L1 ABCA2 LINC01451 C9orf172 LOC101930307 PTGDS TPRN TMEM141 FAM69B C9orf173-AS1 RNF224 LOC100128593

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

positive regulation of T cell cytokine production
protein complex assembly
activation of cysteine-type endopeptidase activity involved in apoptotic process
signal transduction
I-kappaB kinase/NF-kappaB signaling
activation of NF-kappaB-inducing kinase activity
regulation of tumor necrosis factor-mediated signaling pathway
regulation of necrotic cell death
protein catabolic process
positive regulation of interleukin-2 production
tumor necrosis factor-mediated signaling pathway
negative regulation of glial cell apoptotic process
response to endoplasmic reticulum stress
regulation of apoptotic process
positive regulation of JUN kinase activity
cellular protein complex assembly
positive regulation of T cell activation
regulation of immunoglobulin secretion
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
protein heterooligomerization
protein autoubiquitination
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
protein homotrimerization
protein K63-linked ubiquitination
death-inducing signaling complex assembly
cellular response to nitric oxide
positive regulation of protein homodimerization activity
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
programmed necrotic cell death
negative regulation of neuron death
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
positive regulation of tumor necrosis factor-mediated signaling pathway
positive regulation of I-kappaB phosphorylation
positive regulation of extrinsic apoptotic signaling pathway

Function(s)

ubiquitin-protein transferase activity
signal transducer activity
tumor necrosis factor receptor binding
CD40 receptor binding
protein binding
zinc ion binding
ligase activity
enzyme binding
protein kinase binding
protein phosphatase binding
mitogen-activated protein kinase kinase kinase binding
ubiquitin protein ligase binding
thioesterase binding
protein complex binding
identical protein binding
sphingolipid binding