Hs04369269_cn

• Gene Symbol: MIR4479
• Assay Reference Genome Location: Chr.9:136886759 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 100616480
• Gene Name: microRNA 4479
• Gene Aliases: -
• Location: Chr.9:136886733-136886803 on Build GRCh38
• Assay Gene Location:

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MIR4479	NR_039697.1

Target Gene Details

• Entrez Gene ID: 7186
• Gene Name: TNF receptor associated factor 2
• Gene Aliases: MGC:45012, TRAP, TRAP3
• Location: Chr.9:136881776-136926615 on Build GRCh38
• Assay Gene Location: Within Intron 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRAF2	NM_021138.3			NP_066961.2
	XM_011518973.2			XP_011517275.1
	XM_011518976.2			XP_011517278.1
	XM_011518977.2			XP_011517279.1
	AK054686.1			BAB70792.1
	AK222961.1
	AK289722.1
	AK294607.1
	AK298370.1
	BC033810.1			AAH33810.1
	BC043492.1			AAH43492.1
	BM785733.1
	BX538160.1			CAD98040.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv951205	Chr.9:136821949 - 136944648 on Build GRCh38	Deletion	MIR4292 EDF1 C9orf172 MIR4479 PHPT1 RABL6 FBXW5 TRAF2 MAMDC4
nsv818738	Chr.9:136740043 - 137009585 on Build GRCh38	Gain	LCNL1 CCDC183-AS1 RABL6 MAMDC4 MIR4292 LCN8 EDF1 PRR31 ABCA2 CLIC3 FBXW5 TRAF2 CCDC183 LCN6 MIR6722 C8G TMEM141 LCN15 LOC100128593 LCN10 LCN12 C9orf172 MIR4479 PHPT1 C9orf142 PTGDS
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	STPG3 NPDC1 RNF208 RABL6 MIR4292 ABCA2 NSMF CCDC183 ENTPD2 DPP7 FAM166A C8G NRARP SAPCD2 UAP1L1 ANAPC2 LCN12 NOXA1 TUBB4B PHPT1 C9orf142 MIR3621 TMEM203 C9orf139 TOR4A RNF224 LRRC26 GRIN1 LOC101930307 LCNL1 CYSRT1 MAN1B1 TMEM210 MAN1B1-AS1 PNPLA7 CCDC183-AS1 MAMDC4 TPRN SSNA1 EDF1 PRR31 CLIC3 FBXW5 TRAF2 MIR7114 EXD3 SLC34A3 NDOR1 NELFB C9orf172 MIR4479 C9orf173-AS1 FUT7 PTGDS ENTPD8
nsv469918	Chr.9:136359865 - 137173890 on Build GRCh38	Loss	FAM69B SEC16A NALT1 NPDC1 RABL6 SNHG7 HSPC324 MIR4673 MIR4292 ABCA2 LINC01451 C9orf163 CCDC183 ENTPD2 DPP7 MIR6722 C8G PMPCA SAPCD2 UAP1L1 MIR126 LCN12 SNORA17B SNAPC4 PHPT1 C9orf142 MIR3621 SNORA17A C9orf139 CARD9 LRRC26 GRIN1 LOC101930307 LCNL1 MAN1B1 TMEM210 MAN1B1-AS1 CCDC183-AS1 EGFL7 NOTCH1 DNLZ MAMDC4 LCN8 EDF1 PRR31 CLIC3 INPP5E FBXW5 TRAF2 MIR4674 LCN6 TMEM141 LCN15 AGPAT2 LOC100128593 LCN10 C9orf172 MIR4479 FUT7 PTGDS SDCCAG3
esv2759720	Chr.9:136356377 - 136932033 on Build GRCh38	Loss	FAM69B SEC16A NALT1 CARD9 CCDC183-AS1 RABL6 SNHG7 EGFL7 HSPC324 NOTCH1 DNLZ MAMDC4 MIR4673 MIR4292 LCN8 GPSM1 EDF1 LINC01451 INPP5E TRAF2 MIR4674 C9orf163 CCDC183 LCN6 MIR6722 TMEM141 LCN15 PMPCA AGPAT2 LOC100128593 LCN10 MIR126 SNORA17B SNAPC4 C9orf172 MIR4479 PHPT1 SNORA17A SDCCAG3
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	FAM69B STPG3 NPDC1 RNF208 RABL6 SNHG7 HSPC324 MIR4292 ABCA2 LINC01451 CCDC183 ENTPD2 DPP7 FAM166A MIR6722 C8G NRARP SAPCD2 UAP1L1 MIR126 ANAPC2 LCN12 TUBB4B SNORA17B PHPT1 C9orf142 MIR3621 TMEM203 SNORA17A C9orf139 TOR4A RNF224 LRRC26 GRIN1 LOC101930307 LCNL1 CYSRT1 MAN1B1 TMEM210 MAN1B1-AS1 CCDC183-AS1 EGFL7 MAMDC4 TPRN SSNA1 LCN8 EDF1 PRR31 CLIC3 FBXW5 TRAF2 LCN6 EXD3 TMEM141 LCN15 AGPAT2 LOC100128593 LCN10 SLC34A3 NDOR1 NELFB C9orf172 MIR4479 C9orf173-AS1 FUT7 PTGDS

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

positive regulation of T cell cytokine production
protein complex assembly
activation of cysteine-type endopeptidase activity involved in apoptotic process
signal transduction
I-kappaB kinase/NF-kappaB signaling
activation of NF-kappaB-inducing kinase activity
regulation of tumor necrosis factor-mediated signaling pathway
regulation of necrotic cell death
protein catabolic process
positive regulation of interleukin-2 production
tumor necrosis factor-mediated signaling pathway
negative regulation of glial cell apoptotic process
response to endoplasmic reticulum stress
regulation of apoptotic process
positive regulation of JUN kinase activity
cellular protein complex assembly
positive regulation of T cell activation
regulation of immunoglobulin secretion
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
protein heterooligomerization
protein autoubiquitination
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
protein homotrimerization
protein K63-linked ubiquitination
death-inducing signaling complex assembly
cellular response to nitric oxide
positive regulation of protein homodimerization activity
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
programmed necrotic cell death
negative regulation of neuron death
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
positive regulation of tumor necrosis factor-mediated signaling pathway
positive regulation of I-kappaB phosphorylation
positive regulation of extrinsic apoptotic signaling pathway

Function(s)

ubiquitin-protein transferase activity
signal transducer activity
tumor necrosis factor receptor binding
CD40 receptor binding
protein binding
zinc ion binding
ligase activity
enzyme binding
protein kinase binding
protein phosphatase binding
mitogen-activated protein kinase kinase kinase binding
ubiquitin protein ligase binding
thioesterase binding
protein complex binding
identical protein binding
sphingolipid binding