Hs04390158_cn

• Gene Symbol: SLC22A18
• Assay Reference Genome Location: Chr.11:2901418 on build GRCh38
• Cytoband: 11p15.4

Target Gene Details

• Entrez Gene ID: 5002
• Gene Name: solute carrier family 22 member 18
• Gene Aliases: BWR1A, BWSCR1A, HET, IMPT1, ITM, ORCTL2, SLC22A1L, TSSC5, p45-BWR1A
• Location: Chr.11:2899721-2925246 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SLC22A18	NM_183233.2			NP_899056.2
	BC015571.2			AAH15571.1

Target Gene Details

• Entrez Gene ID: 5003
• Gene Name: solute carrier family 22 member 18 antisense
• Gene Aliases: BWR1B, BWSCR1B, ORCTL2S, SLC22A1LS, p27-BWR1B
• Location: Chr.11:2887344-2905504 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SLC22A18AS	NM_001302862.1			NP_001289791.1
	NM_007105.3			NP_009036.2
	XM_017017832.1			XP_016873321.1
	XM_017017833.1			XP_016873322.1
	XM_017017834.1			XP_016873323.1
	AF037066.1			AAC04789.1
	BC030237.1			AAH30237.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv951292	Chr.11:2792271 - 2927870 on Build GRCh38	Deletion	SLC22A18 CDKN1C SLC22A18AS KCNQ1DN KCNQ1 KCNQ1-AS1
esv2759795	Chr.11:2767814 - 2942382 on Build GRCh38	Gain	SLC22A18 CDKN1C SLC22A18AS KCNQ1DN KCNQ1 KCNQ1-AS1 PHLDA2
nsv469930	Chr.11:2831299 - 2924715 on Build GRCh38	Loss	SLC22A18 CDKN1C SLC22A18AS KCNQ1DN KCNQ1 KCNQ1-AS1
nsv832050	Chr.11:2868540 - 2963987 on Build GRCh38	Loss	SLC22A18 CDKN1C SLC22A18AS NAP1L4 SNORA54 KCNQ1DN PHLDA2
nsv553111	Chr.11:2842057 - 2904391 on Build GRCh38	Loss	SLC22A18 CDKN1C SLC22A18AS KCNQ1DN KCNQ1 KCNQ1-AS1
nsv467657	Chr.11:2879188 - 2916401 on Build GRCh38	Loss	SLC22A18 CDKN1C SLC22A18AS

More Information

Additional Information:

For this assay, SNP(s) [rs138644124,rs77284315] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

secondary carrier transporter

Gene Ontology Categories:

Process(es)

drug transmembrane transport
excretion
organic cation transport
drug transport
drug export
biological_process

Function(s)

drug transmembrane transporter activity
symporter activity
drug:proton antiporter activity
ubiquitin protein ligase binding
molecular_function