Hs04463100_cn

• Gene Symbol: MAP1LC3B
• Assay Reference Genome Location: Chr.16:87394710 on build GRCh38
• Cytoband: 16q24.2

Target Gene Details

• Entrez Gene ID: 81631
• Gene Name: microtubule associated protein 1 light chain 3 beta
• Gene Aliases: ATG8F, LC3B, MAP1A/1BLC3, MAP1LC3B-a
• Location: Chr.16:87392195-87404774 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MAP1LC3B	NM_022818.4			NP_073729.1
	AF087871.1			AAM10499.1
	AF183417.1			AAG09686.1
	AF303888.1			AAG23182.1
	AK025556.1			BAB15169.1
	AK290956.1
	AK310224.1
	AK310335.1
	AL834298.1			CAD38970.1
	BC018634.2			AAH18634.1
	BC041874.1			AAH41874.1
	BC045759.1			AAH45759.1
	BC067797.1			AAH67797.1
	BG771621.1
	DA577457.1
	DB055844.1
	JN663879.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv499n67	Chr.16:87353978 - 87409229 on Build GRCh38	Gain	ZCCHC14 FBXO31 MAP1LC3B
nsv833320	Chr.16:87315844 - 87501226 on Build GRCh38	Gain	C16orf95 LOC101928659 ZCCHC14 FBXO31 LOC101928737 MAP1LC3B
nsv428330	Chr.16:87336922 - 87633082 on Build GRCh38	Gain	ZCCHC14 FBXO31 LOC101928737 MAP1LC3B JPH3
nsv510694	Chr.16:87276349 - 87400084 on Build GRCh38	Deletion	LOC101928682 C16orf95 LOC101928659 FBXO31 MAP1LC3B

More Information

Additional Information:

For this assay, SNP(s) [rs111964475] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-motor microtubule binding protein

Gene Ontology Categories:

Process(es)

autophagosome assembly
cellular response to nitrogen starvation
macroautophagy
regulation of mitophagy

Function(s)

protein binding
microtubule binding
ubiquitin protein ligase binding