Hs04468515_cn

• Gene Symbol: FDXR
• Assay Reference Genome Location: Chr.17:74870670 on build GRCh38
• Cytoband: 17q25.1

Target Gene Details

• Entrez Gene ID: 2232
• Gene Name: ferredoxin reductase
• Gene Aliases: ADXR
• Location: Chr.17:74862497-74873031 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
FDXR	NM_001258012.3			NP_001244941.2
	NM_001258013.3			NP_001244942.2
	NM_001258014.3			NP_001244943.2
	NM_001258015.2			NP_001244944.1
	NM_004110.5			NP_004101.3
	NM_024417.4			NP_077728.3
	NR_047576.2
	XM_006721772.1			XP_006721835.1
	XM_011524527.1			XP_011522829.1
	XM_011524528.1			XP_011522830.1
	XM_011524529.1			XP_011522831.1
	AK094120.1
	AK098648.1
	AK223530.1			BAD97250.1
	AK293208.1
	AK293210.1
	AK295307.1
	AK298908.1
	AK301779.1
	BC002960.1			AAH02960.1
	BC063493.1			AAH63493.1
	BT006684.1			AAP35330.1
	DA267443.1
	J03826.1			AAB59497.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833540	Chr.17:74838971 - 75019365 on Build GRCh38	Loss	FADS6 MRPL58 USH1G GRIN2C OTOP3 TMEM104 HID1 HID1-AS1 CDR2L FDXR OTOP2
nsv518292	Chr.17:74810882 - 74982818 on Build GRCh38	Loss	FADS6 USH1G GRIN2C OTOP3 TMEM104 HID1 HID1-AS1 FDXR OTOP2
nsv952367	Chr.17:74751962 - 74961105 on Build GRCh38	Deletion	FADS6 USH1G GRIN2C OTOP3 TMEM104 HID1 FDXR SLC9A3R1 OTOP2 NAT9

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

oxidoreductase

Gene Ontology Categories:

Process(es)

generation of precursor metabolites and energy
steroid biosynthetic process
C21-steroid hormone biosynthetic process
cholesterol metabolic process
sterol metabolic process
oxidation-reduction process

Function(s)

ferredoxin-NADP+ reductase activity
protein binding
NADPH-adrenodoxin reductase activity