Hs04542495_cn

• Gene Symbol: PRDX1
• Assay Reference Genome Location: Chr.1:45521426 on build GRCh38
• Cytoband: 1p34.1

Target Gene Details

• Entrez Gene ID: 5052
• Gene Name: peroxiredoxin 1
• Gene Aliases: MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2
• Location: Chr.1:45511035-45522890 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PRDX1	NM_001202431.1			NP_001189360.1
	NM_002574.3			NP_002565.1
	NM_181696.2			NP_859047.1
	NM_181697.2			NP_859048.1
	AK131049.1
	AK311898.1
	AV691526.1
	BC007063.1			AAH07063.1
	BC021683.1			AAH21683.1
	BM740381.1
	BM762399.1
	BM787105.1
	BM827394.1
	BU564066.1
	CD638470.1
	L19184.1			AAA50464.1
	X67951.1			CAA48137.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3893512	Chr.1:45476180 - 46068871 on Build GRCh38	Gain	MMACHC TESK2 PRDX1 PIK3R3 IPP NASP TMEM69 RPS15AP10 CCDC17 MAST2 GPBP1L1 CCDC163P AKR1A1
nsv829726	Chr.1:45431909 - 45637514 on Build GRCh38	Loss	MMACHC TESK2 CCDC17 PRDX1 GPBP1L1 CCDC163P NASP AKR1A1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

peroxidase

Gene Ontology Categories:

Process(es)

response to reactive oxygen species
skeletal system development
retina homeostasis
cell proliferation
removal of superoxide radicals
regulation of stress-activated MAPK cascade
erythrocyte homeostasis
natural killer cell mediated cytotoxicity
regulation of NF-kappaB import into nucleus
hydrogen peroxide catabolic process
cell redox homeostasis
oxidation-reduction process
cell-cell adhesion

Function(s)

peroxidase activity
protein binding
thioredoxin peroxidase activity
identical protein binding
poly(A) RNA binding
cadherin binding involved in cell-cell adhesion