Hs04546158_cn

• Gene Symbol: CHI3L1
• Assay Reference Genome Location: Chr.1:203186171 on build GRCh38
• Cytoband: 1q32.1

Target Gene Details

• Entrez Gene ID: 1116
• Gene Name: chitinase 3 like 1
• Gene Aliases: ASRT7, CGP-39, GP-39, GP39, HC-gp39, HCGP-3P, YKL-40, YKL40, YYL-40, hCGP-39
• Location: Chr.1:203178931-203186794 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CHI3L1	NM_001276.2			NP_001267.2
	AK130142.1
	AK130200.1
	AK225266.1
	AK225584.1
	AK312911.1
	BC008568.1			AAH08568.1
	BC038354.1			AAH38354.1
	BC039132.1			AAH39132.1
	BT007223.1			AAP35887.1
	DA167112.1
	M80927.1			AAA16074.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv952639	Chr.1:203164873 - 203186672 on Build GRCh38	Deletion	MYBPH ADORA1 CHI3L1
nsv832370	Chr.1:202997191 - 203196105 on Build GRCh38	Loss	PPFIA4 TMEM183A MYBPH ADORA1 LOC100506747 MYOG CHI3L1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

glycosidase

Gene Ontology Categories:

Process(es)

carbohydrate metabolic process
chitin catabolic process
apoptotic process
inflammatory response
activation of NF-kappaB-inducing kinase activity
response to mechanical stimulus
positive regulation of peptidyl-threonine phosphorylation
lung development
response to tumor necrosis factor
positive regulation of angiogenesis
cartilage development
positive regulation of protein kinase B signaling
positive regulation of ERK1 and ERK2 cascade
response to interleukin-1
response to interleukin-6
cellular response to interleukin-1
cellular response to tumor necrosis factor
interleukin-8 secretion

Function(s)

chitinase activity
extracellular matrix structural constituent
chitin binding
carbohydrate binding