Hs04676639_cn

• Gene Symbol: IL36B
• Assay Reference Genome Location: Chr.2:113050843 on build GRCh38
• Cytoband: 2q14.1

Target Gene Details

• Entrez Gene ID: 27177
• Gene Name: interleukin 36, beta
• Gene Aliases: FIL1, FIL1-(ETA), FIL1H, FILI-(ETA), IL-1F8, IL-1H2, IL1-ETA, IL1F8, IL1H2
• Location: Chr.2:113022091-113052867 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
IL36B	NM_014438.4			NP_055253.2
	NM_173178.2			NP_775270.1
	AF200494.1			AAF69250.1
	AF201833.1			AAF25213.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv2881	Chr.2:113043228 - 113089020 on Build GRCh38	Deletion	IL36RN IL1F10 IL36B
nsv582709	Chr.2:113047167 - 113052485 on Build GRCh38	Loss	IL36B

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

interleukin superfamily

Gene Ontology Categories:

Process(es)

inflammatory response
immune response
cytokine-mediated signaling pathway
positive regulation of interleukin-6 production
innate immune response
positive regulation of T cell differentiation

Function(s)

cytokine activity
interleukin-1 receptor binding