Hs05033529_cn

• Gene Symbol: GSR
• Assay Reference Genome Location: Chr.8:30678272 on build GRCh38
• Cytoband: 8p12

Target Gene Details

• Entrez Gene ID: 2936
• Gene Name: glutathione-disulfide reductase
• Gene Aliases: HEL-75, HEL-S-122m
• Location: Chr.8:30678061-30727969 on Build GRCh38
• Assay Gene Location: Within Exon 13

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GSR	NM_000637.3	13	2951	NP_000628.2
	NM_001195102.1	12	2864	NP_001182031.1
	NM_001195103.1	12	2792	NP_001182032.1
	NM_001195104.1	11	2705	NP_001182033.1
	CA944703.1	1	224

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2671289	Chr.8:30677728 - 30678875 on Build GRCh38	Deletion	GSR
nsv516544	Chr.8:30678143 - 30703370 on Build GRCh38	Loss	GSR
esv3616792	Chr.8:30677571 - 30678955 on Build GRCh38	Loss	GSR
esv2657353	Chr.8:30677311 - 30679064 on Build GRCh38	Deletion	GSR

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

oxidoreductase, reductase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

response to reactive oxygen species
glutathione metabolic process
nucleobase-containing small molecule interconversion
cell redox homeostasis
oxidation-reduction process
cellular oxidant detoxification

Function(s)

glutathione-disulfide reductase activity
electron carrier activity
flavin adenine dinucleotide binding
NADP binding