Hs05141570_cn

• Gene Symbol: IL2RA
• Assay Reference Genome Location: Chr.10:6022155 on build GRCh38
• Cytoband: 10p15.1

Target Gene Details

• Entrez Gene ID: 3559
• Gene Name: interleukin 2 receptor subunit alpha
• Gene Aliases: CD25, IDDM10, IL2R, IMD41, TCGFR, p55
• Location: Chr.10:6010694-6062370 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
IL2RA	NM_000417.2			NP_000408.1
	NM_001308242.1			NP_001295171.1
	NM_001308243.1			NP_001295172.1
	AF008556.1			AAB63458.1
	AK223313.1			BAD97033.1
	AK313847.1
	CR996090.1
	K03122.1			AAB59535.1
	M14098.1			AAA59142.1
	X01057.1			CAA25525.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv525927	Chr.10:6017935 - 6036116 on Build GRCh38	Loss	IL2RA
dgv1e49	Chr.10:5684858 - 6183224 on Build GRCh38	Loss	FBXO18 FAM208B MIR3155B MIR3155A RBM17 IL15RA ANKRD16 IL2RA PFKFB3 GDI2

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

MAPK cascade
inflammatory response to antigenic stimulus
regulation of T cell tolerance induction
apoptotic process
activation-induced cell death of T cells
inflammatory response
immune response
cell surface receptor signaling pathway
Notch signaling pathway
cell proliferation
interleukin-2-mediated signaling pathway
positive regulation of activated T cell proliferation
negative regulation of T cell proliferation
positive regulation of GTPase activity
positive regulation of T cell differentiation
regulation of T cell homeostatic proliferation
negative regulation of defense response to virus
negative regulation of inflammatory response
negative regulation of immune response

Function(s)

interleukin-2 receptor activity
Ras guanyl-nucleotide exchange factor activity
drug binding
interleukin-2 binding