Hs05193375_cn

• Gene Symbol: ARID5B
• Assay Reference Genome Location: Chr.10:61914208 on build GRCh38
• Cytoband: 10q21.2

Target Gene Details

• Entrez Gene ID: 84159
• Gene Name: AT-rich interaction domain 5B
• Gene Aliases: DESRT, MRF-2, MRF2
• Location: Chr.10:61901254-62096948 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ARID5B	NM_032199.2			NP_115575.1
	XM_011540262.1			XP_011538564.1
	AK296921.1
	BC107800.1			AAI07801.1
	BG615173.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv8681	Chr.10:61896798 - 62671529 on Build GRCh38	Gain	RTKN2 LOC283045 ARID5B ZNF365

More Information

Additional Information:

For this assay, SNP(s) [rs76459615] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transcription cofactor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
kidney development
liver development
transcription, DNA-templated
male gonad development
female gonad development
post-embryonic development
fibroblast migration
histone demethylation
adrenal gland development
multicellular organism growth
fat cell differentiation
negative regulation of transcription, DNA-templated
platelet-derived growth factor receptor signaling pathway
cell development
muscle organ morphogenesis
skeletal system morphogenesis
positive regulation of sequence-specific DNA binding transcription factor activity
palate development
face morphogenesis
adipose tissue development
fat pad development

Function(s)

RNA polymerase II regulatory region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription coactivator activity
protein binding
histone demethylase activity
transcription regulatory region DNA binding