Hs05212642_cn

• Gene Symbol: NRG3
• Assay Reference Genome Location: Chr.10:82231993 on build GRCh38
• Cytoband: 10q23.1

Target Gene Details

• Entrez Gene ID: 10718
• Gene Name: neuregulin 3
• Gene Aliases: HRG3, pro-NRG3
• Location: Chr.10:81875298-82989979 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NRG3	NM_001010848.3			NP_001010848.2
	NM_001165972.1			NP_001159444.1
	NM_001165973.1			NP_001159445.1
	XM_005269444.4			XP_005269501.1
	XM_011539172.2			XP_011537474.1
	XM_011539173.2			XP_011537475.1
	XM_011539175.2			XP_011537477.1
	XM_017015573.1			XP_016871062.1
	XM_017015574.1			XP_016871063.1
	XM_017015575.1			XP_016871064.1
	XM_017015576.1			XP_016871065.1
	XM_017015577.1			XP_016871066.1
	XM_017015578.1			XP_016871067.1
	XM_017015579.1			XP_016871068.1
	XM_017015580.1			XP_016871069.1
	XM_017015581.1			XP_016871070.1
	XM_017015582.1			XP_016871071.1
	XM_017015583.1			XP_016871072.1
	XM_017015584.1			XP_016871073.1
	AK122886.1
	AK296563.1
	BC136811.1
	DQ001411.1			AAY17216.1
	DQ338459.1			ABC69293.1
	DQ857894.1
	HM068873.1
	HM068874.1
	HM068875.1
	HM068876.1
	HM068877.1
	HM068878.1
	HM068879.1
	HM068880.1
	HM068881.1
	HM068882.1
	HM068883.1
	HM068884.1

Target Gene Details

• Entrez Gene ID: 101929590
• Gene Name: NRG3 antisense RNA 1
• Gene Aliases: C10orf100, Em:AC010157.1
• Location: Chr.10:82229014-82232920 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NRG3-AS1	NR_120666.1
	AA383013.1
	CF272718.1
	CR737767.1
	DB052745.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv551704	Chr.10:82136504 - 82268652 on Build GRCh38	Loss	NRG3 NRG3-AS1
esv3891873	Chr.10:81025608 - 82340753 on Build GRCh38	Gain	NRG3 NRG3-AS1
esv3891875	Chr.10:82171786 - 82294496 on Build GRCh38	Loss	NRG3 NRG3-AS1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

growth factor

Gene Ontology Categories:

Process(es)

regulation of cell growth
activation of transmembrane receptor protein tyrosine kinase activity
pattern specification process
chemorepulsion involved in interneuron migration from the subpallium to the cortex
intracellular signal transduction
animal organ development
mammary placode formation
negative regulation of neuron migration

Function(s)

receptor binding
growth factor activity
transmembrane receptor protein tyrosine kinase activator activity
receptor tyrosine kinase binding
chemorepellent activity