Hs05355250_cn

• Gene Symbol: DYX1C1
• Assay Reference Genome Location: Chr.15:55490618 on build GRCh38
• Cytoband: 15q21.3

Target Gene Details

• Entrez Gene ID: 161582
• Gene Name: dyslexia susceptibility 1 candidate 1
• Gene Aliases: CILD25, DNAAF4, DYX1, DYXC1, EKN1, RD
• Location: Chr.15:55417755-55508234 on Build GRCh38
• Assay Gene Location: Within Intron 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DYX1C1	NM_001033559.2			NP_001028731.1
	NM_001033560.1			NP_001028732.1
	NM_130810.3			NP_570722.2
	AF337549.1			AAL73230.1
	AK095201.1			BAC04498.1
	AK302316.1
	BC062564.1			AAH62564.1
	KU178882.1
	KU178883.1
	KU178884.1

Target Gene Details

• Entrez Gene ID: 100533483
• Gene Name: DYX1C1-CCPG1 readthrough (NMD candidate)
• Gene Aliases: -
• Location: Chr.15:55355223-55498584 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DYX1C1-CCPG1	NR_037923.1
	AK295788.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2761899	Chr.15:53592144 - 55643724 on Build GRCh38	Gain+Loss	DYX1C1 RSL24D1 LOC107984745 PIGBOS1 C15orf65 CCPG1 DYX1C1-CCPG1 UNC13C PRTG LOC105370829 PYGO1 MIR628 RAB27A PIGB WDR72
esv3636565	Chr.15:55484284 - 55490748 on Build GRCh38	Loss	DYX1C1-CCPG1 DYX1C1
nsv1542	Chr.15:55461944 - 55496407 on Build GRCh38	Insertion	DYX1C1-CCPG1 DYX1C1
nsv569523	Chr.15:55263404 - 55544506 on Build GRCh38	Gain	DYX1C1-CCPG1 DYX1C1 PYGO1 LOC107984745 PIGBOS1 C15orf65 MIR628 CCPG1 RAB27A PIGB
nsv1043789	Chr.15:55108674 - 55800256 on Build GRCh38	Gain	DYX1C1-CCPG1 DYX1C1 RSL24D1 PRTG PYGO1 LOC107984745 PIGBOS1 C15orf65 MIR628 CCPG1 RAB27A PIGB
nsv569539	Chr.15:55430015 - 55963576 on Build GRCh38	Loss	DYX1C1-CCPG1 DYX1C1 PRTG PYGO1 LOC107984745 NEDD4
nsv833016	Chr.15:55456971 - 55605708 on Build GRCh38	Gain	DYX1C1-CCPG1 DYX1C1 PYGO1 LOC107984745

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

chaperone

Gene Ontology Categories:

Process(es)

neuron migration
cilium movement
determination of left/right symmetry
regulation of intracellular estrogen receptor signaling pathway
outer dynein arm assembly
inner dynein arm assembly
regulation of proteasomal protein catabolic process

Function(s)

protein binding
estrogen receptor binding