Hs05392803_cn

• Gene Symbol: PLCB2
• Assay Reference Genome Location: Chr.15:40286061 on build GRCh38
• Cytoband: 15q15.1

Target Gene Details

• Entrez Gene ID: 5330
• Gene Name: phospholipase C beta 2
• Gene Aliases: PLC-beta-2
• Location: Chr.15:40285496-40307973 on Build GRCh38
• Assay Gene Location: Overlaps Intron 34 - Exon 35

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PLCB2	XM_017022319.1			XP_016877808.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv510660	Chr.15:40260705 - 40429684 on Build GRCh38	Deletion	BUB1B-PAK6 ANKRD63 C15orf52 IVD PLCB2 PHGR1 INAFM2 KNSTRN DISP2 PAK6
nsv471240	Chr.15:40235954 - 40303426 on Build GRCh38	Loss	BUB1B-PAK6 ANKRD63 PLCB2 C15orf56 PAK6
nsv457118	Chr.15:40273504 - 40314283 on Build GRCh38	Loss	BUB1B-PAK6 ANKRD63 PLCB2 PAK6
esv34145	Chr.15:40257416 - 40597626 on Build GRCh38	Loss	RPUSD2 C15orf57 ANKRD63 C15orf52 PHGR1 INAFM2 KNSTRN BAHD1 BUB1B-PAK6 KNL1 IVD MRPL42P5 CHST14 PLCB2 DISP2 PAK6
nsv517541	Chr.15:40265067 - 40303426 on Build GRCh38	Loss	BUB1B-PAK6 ANKRD63 PLCB2 PAK6

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

phospholipase

Gene Ontology Categories:

Process(es)

phospholipid metabolic process
activation of phospholipase C activity
Wnt signaling pathway, calcium modulating pathway
lipid catabolic process
intracellular signal transduction
inositol phosphate metabolic process
sensory perception of bitter taste

Function(s)

phosphatidylinositol phospholipase C activity
phospholipase C activity
signal transducer activity
calcium ion binding