Hs05398568_cn

• Gene Symbol: DPEP1
• Assay Reference Genome Location: Chr.16:89616350 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 1800
• Gene Name: dipeptidase 1 (renal)
• Gene Aliases: MBD1, MDP, RDP
• Location: Chr.16:89613308-89641540 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DPEP1	NM_001128141.2			NP_001121613.1
	XM_005256285.4			XP_005256342.1
	AK309577.1
	BM152944.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv952078	Chr.16:89602793 - 89640192 on Build GRCh38	Deletion	DPEP1
nsv1057351	Chr.16:89610380 - 89707988 on Build GRCh38	Loss	SPATA2L DPEP1 CDK10 VPS9D1 SPATA33 CHMP1A
nsv1929	Chr.16:89601681 - 89628517 on Build GRCh38	Insertion	DPEP1
nsv428331	Chr.16:89216635 - 90185980 on Build GRCh38	Gain+Loss	URAHP DPEP1 CDK10 RPL13 LOC100287036 TUBB8P7 FANCA AFG3L1P ZNF276 ANKRD11 SPATA33 SPG7 MC1R GAS8-AS1 DBNDD1 VPS9D1-AS1 LOC105371419 GAS8 TUBB3 LOC105371414 TCF25 LOC101927817 CHMP1A SNORD68 VPS9D1 PRDM7 CPNE7 SPIRE2 LOC107984817 SPATA2L CENPBD1 ZNF778 DEF8 FAM157C
nsv573738	Chr.16:89549357 - 89625890 on Build GRCh38	Loss	SNORD68 DPEP1 RPL13 CPNE7 SPG7
nsv1063483	Chr.16:89347250 - 89661187 on Build GRCh38	Gain	SNORD68 DPEP1 RPL13 CPNE7 LOC101927817 ANKRD11 SPATA33 CHMP1A SPG7
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	CDH15 CDK10 RPL13 LOC100287036 TUBB8P7 FANCA SNAI3 AFG3L1P ZNF276 RNF166 LOC400558 SPATA33 MC1R PABPN1L DBNDD1 IL17C CBFA2T3 LOC105371419 TUBB3 TCF25 CDT1 CTU2 LOC100129697 VPS9D1 TRAPPC2L CPNE7 SPIRE2 LOC107984817 SPATA2L SLC22A31 LOC100289580 FAM157C URAHP DPEP1 ANKRD11 LINC00304 SNAI3-AS1 SPG7 GAS8-AS1 VPS9D1-AS1 APRT LOC105371409 CYBA GAS8 LOC105371414 LOC107987238 MIR4722 GALNS LOC101927817 CHMP1A SNORD68 LOC101927793 PIEZO1 PRDM7 ACSF3 CENPBD1 LOC339059 ZNF778 MVD DEF8
nsv509639	Chr.16:89513538 - 89775915 on Build GRCh38	Insertion	SNORD68 DPEP1 CDK10 VPS9D1 RPL13 CPNE7 FANCA ZNF276 SPATA33 SPG7 SPATA2L VPS9D1-AS1 CHMP1A
nsv1066382	Chr.16:89537178 - 89661187 on Build GRCh38	Gain	SNORD68 DPEP1 RPL13 CPNE7 SPATA33 CHMP1A SPG7

More Information

Additional Information:

For this assay, SNP(s) [rs74429256] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

proteolysis
leukotriene metabolic process
glutathione metabolic process
xenobiotic metabolic process
apoptotic process
antibiotic metabolic process
negative regulation of cell migration
cellular response to drug
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
homocysteine metabolic process
cellular response to calcium ion
cellular response to nitric oxide
cellular lactam catabolic process

Function(s)

protein binding
metalloexopeptidase activity
dipeptidyl-peptidase activity
zinc ion binding
dipeptidase activity
GPI anchor binding
cysteine-type endopeptidase inhibitor activity involved in apoptotic process
metallodipeptidase activity
modified amino acid binding