Hs05398568_cn

• Gene Symbol: DPEP1
• Assay Reference Genome Location: Chr.16:89616350 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 1800
• Gene Name: dipeptidase 1 (renal)
• Gene Aliases: MBD1, MDP, RDP
• Location: Chr.16:89613308-89641540 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DPEP1	NM_001128141.2			NP_001121613.1
	XM_005256285.4			XP_005256342.1
	AK309577.1
	BM152944.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2762221	Chr.16:89610380 - 90039318 on Build GRCh38	Gain+Loss	VPS9D1 DEF8 VPS9D1-AS1 GAS8-AS1 LOC105371419 CDK10 SPATA33 FANCA TCF25 TUBB3 LOC107984817 ZNF276 AFG3L1P SPIRE2 DPEP1 MC1R CENPBD1 SPATA2L CHMP1A GAS8 DBNDD1
nsv952078	Chr.16:89602793 - 89640192 on Build GRCh38	Deletion	DPEP1
nsv1929	Chr.16:89601681 - 89628517 on Build GRCh38	Insertion	DPEP1
nsv428331	Chr.16:89216635 - 90185980 on Build GRCh38	Gain+Loss	VPS9D1-AS1 PRDM7 ANKRD11 GAS8-AS1 LOC105371419 CDK10 SPATA33 TCF25 TUBB8P7 LOC100287036 AFG3L1P DPEP1 URAHP SPATA2L CHMP1A DBNDD1 RPL13 FAM157C VPS9D1 DEF8 SPG7 FANCA TUBB3 LOC107984817 LOC105371414 ZNF276 SPIRE2 LOC101927817 MC1R SNORD68 CENPBD1 GAS8 CPNE7 ZNF778
nsv573738	Chr.16:89549357 - 89625890 on Build GRCh38	Loss	DPEP1 SPG7 SNORD68 CPNE7 RPL13
nsv1063483	Chr.16:89347250 - 89661187 on Build GRCh38	Gain	DPEP1 LOC101927817 ANKRD11 SPG7 SNORD68 SPATA33 CHMP1A CPNE7 RPL13
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	LOC100289580 ANKRD11 LOC105371419 CDK10 SPATA33 TUBB8P7 LOC105371409 DPEP1 CYBA MVD SNAI3 CBFA2T3 PIEZO1 URAHP SPATA2L CHMP1A IL17C SNAI3-AS1 SPG7 LOC400558 FANCA TUBB3 CDH15 LOC107984817 SPIRE2 PABPN1L MIR4722 CPNE7 VPS9D1-AS1 PRDM7 GALNS GAS8-AS1 TRAPPC2L RNF166 LOC339059 TCF25 SLC22A31 LOC100287036 AFG3L1P CTU2 CDT1 LINC00304 DBNDD1 RPL13 FAM157C APRT LOC101927793 VPS9D1 ACSF3 DEF8 LOC100129697 LOC107987238 LOC105371414 ZNF276 LOC101927817 MC1R SNORD68 CENPBD1 GAS8 ZNF778
nsv509639	Chr.16:89513538 - 89775915 on Build GRCh38	Insertion	VPS9D1 VPS9D1-AS1 SPG7 CDK10 SPATA33 FANCA ZNF276 DPEP1 SNORD68 SPATA2L CHMP1A CPNE7 RPL13
nsv1066382	Chr.16:89537178 - 89661187 on Build GRCh38	Gain	DPEP1 SPG7 SNORD68 SPATA33 CHMP1A CPNE7 RPL13

More Information

Additional Information:

For this assay, SNP(s) [rs74429256] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

proteolysis
leukotriene metabolic process
glutathione metabolic process
xenobiotic metabolic process
apoptotic process
antibiotic metabolic process
negative regulation of cell migration
cellular response to drug
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
homocysteine metabolic process
cellular response to calcium ion
cellular response to nitric oxide
cellular lactam catabolic process

Function(s)

protein binding
metalloexopeptidase activity
dipeptidyl-peptidase activity
zinc ion binding
dipeptidase activity
GPI anchor binding
cysteine-type endopeptidase inhibitor activity involved in apoptotic process
metallodipeptidase activity
modified amino acid binding