Hs05437164_cn

• Gene Symbol: NLRC3
• Assay Reference Genome Location: Chr.16:3556434 on build GRCh38
• Cytoband: 16p13.3

Target Gene Details

• Entrez Gene ID: 197358
• Gene Name: NLR family CARD domain containing 3
• Gene Aliases: CLR16.2, NOD3
• Location: Chr.16:3538272-3578373 on Build GRCh38
• Assay Gene Location: Within Intron 12

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NLRC3	NM_178844.3			NP_849172.2
	NR_075083.2
	XM_017023027.1			XP_016878516.1
	XM_017023028.1			XP_016878517.1
	XM_017023029.1			XP_016878518.1
	XM_017023030.1			XP_016878519.1
	XM_017023031.1			XP_016878520.1
	XM_017023032.1			XP_016878521.1
	XM_017023033.1			XP_016878522.1
	XM_017023034.1			XP_016878523.1
	XM_017023035.1			XP_016878524.1
	XM_017023036.1			XP_016878525.1
	XM_017023037.1			XP_016878526.1
	XM_017023038.1			XP_016878527.1
	XM_017023039.1			XP_016878528.1
	AF501291.1			AAM22459.1
	AF501292.1			AAM22460.1
	AK074109.1			BAB84935.1
	AK090431.1			BAC03412.1
	AK090476.1			BAC03457.1
	AY601811.1			AAT48367.1
	FJ889357.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833128	Chr.16:3525122 - 3690497 on Build GRCh38	Loss	TRAP1 CLUAP1 DNASE1 LOC101929732 NLRC3 SLX4
nsv517451	Chr.16:3549655 - 3611814 on Build GRCh38	Loss	DNASE1 LOC101929732 NLRC3 SLX4

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

I-kappaB kinase/NF-kappaB signaling
negative regulation of NF-kappaB transcription factor activity
negative regulation of interleukin-6 production
negative regulation of tumor necrosis factor production
T cell activation
negative regulation of I-kappaB kinase/NF-kappaB signaling

Function(s)

molecular_function
ATP binding